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(R)-Perharidine-1

A potent CDK inhibitor
Catalog #: 2615
SKU-Size Size Price Qty
2615-1 1 mg
$105.00
2615-5 5 mg
$425.00
More Sizes Get Quote

Product Details

Alternate Name (R)-2-((3-Isopropyl)-7-(4-pyridin-2-yl)benzylamino)-3H-imidazo[4,5-b]pyridine-5-yl)amino)butan-1-ol
Appearance White to off-white solid
CAS # 1133437-80-5
Molecular Formula C₂₅H₃₀N₆O
Molecular Weight 430.55
Purity >95% by NMR
Solubility DMSO or EtOH
SMILES CC[[email protected]](CO)NC1=CC(NCC2=CC=C(C3=NC=CC=C3)C=C2)=C4C(N(C(C)C)C=N4)=N1
InChi InChI=1S/C25H30N6O/c1-4-20(15-32)29-23-13-22(24-25(30-23)31(16-28-24)17(2)3)27-14-18-8-10-19(11-9-18)21-7-5-6-12-26-21/h5-13,16-17,20,32H,4,14-15H2,1-3H3,(H2,27,29,30)/t20-/m1/s1
InChi Key VGHHVXRBOQENRA-HXUWFJFHSA-N
Handling Protect from air and light
Storage Conditions -20 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

(R)-Perharidine-1 is a potent and selective inhibitor of cyclin dependent kinases CDK1, CDK2, CDK5 and CDK9. Apoptosis inducer . Also acts as a casein kinase 1 (CK1δ/ε) inhibitor. Inhibits the proliferation of various cancer cell lines.


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