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Quinol 1h

A potent and selective antitumor agent
Catalog #: 2436
SKU-Size Size Price Qty
2436-5 5 mg
$145.00
2436-25 25 mg
$545.00
More Sizes Get Quote

Product Details

Alternate Name 4-(1-Benzenesulfonyl-6-fluoro-1H-indol-2-yl)-4-hydroxy-cyclohexa-2,5-dienone
Appearance Crystalline solid
Molecular Formula C₂₀H₁₄FNO₄S
Molecular Weight 383.4
Purity ≥98% by HPLC
Solubility DMSO
SMILES O=C(C=C1)C=CC1(O)C2=CC3=C(N2S(=O)(C4=CC=CC=C4)=O)C=CC=C3
InChi InChI=1S/C20H15NO4S/c22-16-10-12-20(23,13-11-16)19-14-15-6-4-5-9-18(15)21(19)26(24,25)17-7-2-1-3-8-17/h1-14,23H
InChi Key HWKQYGBAAMKHDY-UHFFFAOYSA-N
Handling Protect from light and air
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A potent and selective antitumor agent that displays potent activity against renal, colon, and breast cancer cell lines in the NCI 60-cell panel. Exhibits a mean GI₅₀ of 16 nM and a mean LC₅₀ value of 2.24 µM in NCI60-cell-line screen, with LC₅₀ activity in the HCT 116 human colon cancer cell line below 10 nM.


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