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Qstatin

Qstatin is a potent and selective inhibitor of quorum sensing (QS) in vibrio species
Catalog #: B2618
SKU-Size Size Price Qty
B2618-5 5 mg
$95.00
B2618-25 25 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name 1-(5-Bromothiophene-2-sulfonyl)-1H-pyrazole, Q-statin
Appearance Crystalline solid
CAS # 902688-24-8
Molecular Formula C₇H₅BrN₂O₂S₂
Molecular Weight 293.15
Purity ≥98% by HPLC
Solubility in DMSO
SMILES O=S(N1N=CC=C1)(C2=CC=C(Br)S2)=O
InChi InChI=1S/C7H5BrN2O2S2/c8-6-2-3-7(13-6)14(11,12)10-5-1-4-9-10/h1-5H
InChi Key MLRBBGFHILYDBK-UHFFFAOYSA-N
PubChem CID 3237735
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Qstatin is a potent, and selective Vibrio QS inhibitor which affects Vibrio harveyi LuxR homologues, the well-conserved master transcriptional regulators for QS in Vibrio species. QStatin binds tightly to a putative ligand-binding pocket in SmcR, the LuxR homologue in V. vulnificus, and changes the flexibility of the protein, thereby altering its transcription regulatory activity.


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