Product Details
| abID | ab141408 |
|---|---|
| Cat # +Size | 1680-5 |
| Size | 5 mg |
| Alternate Name | (2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol |
| Appearance | White solid |
| CAS # | 944328-88-5 |
| Molecular Formula | C₃₆H₃₃N₅O₂ |
| Molecular Weight | 567.68 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (>10 mg/ml) |
| SMILES | C1CC2=C(C1)C=C(C=C2)OC3=NC4=C(C(=N3)NC(CC5=CC=CC=C5)CO)N=CN4CC6=CC=C(C=C6)C7=CC=CC=C7 |
| InChi | InChI=1S/C36H33N5O2/c42-23-31(20-25-8-3-1-4-9-25)38-34-33-35(40-36(39-34)43-32-19-18-28-12-7-13-30(28)21-32)41(24-37-33)22-26-14-16-29(17-15-26)27-10-5-2-6-11-27/h1-6,8-11,14-19,21,24,31,42H,7,12-13,20,22-23H2,(H,38,39,40)/t31-/m0/s1 |
| InChi Key | DOKZLKDGUQWMSX-HKBQPEDESA-N |
| PubChem CID | 42623900 |
| MDL Number | MFCD12912439 |
| Handling | Protect from air and moisture |
| Storage Conditions | 4°C |
| Shipping Conditions | RT |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Inhibits the GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) as well as synergizes the Wnt/β-catenin signaling pathway. The Wnt/β-catenin signaling pathway regulates cell fate and behavior during embryogenesis, adult tissue homeostasis, and regeneration.
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