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Pyruvate Carboxylase, Rhizobium etli Recombinant

A ligase enzyme that has a crucial role in gluconeogenesis and lipogenesis in mammals
Catalog #: P1661
SKU-Size Size Price Qty
P1661-10 10 μg
P1661-50 50 μg
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Product Details

Alternate Name Pyruvic carboxylase, PC, EC; Pyruvate Carboxylase, Recombinant
Accession # Q59740, aa (2-1154)
Source E. coli
Appearance Liquid
Molecular Weight 127.8 kDa (with C-terminal His-tag)
Purity by SDS-PAGE ≥ 90 %
Biological Activity Biological activity was determined using BioVision’s Pyruvate carboxylase Activity Assay Kit (Colorimetric) (BV Catalog # K2075-100).
Amino Acid Sequence aa (2-1154)
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not For Use in Humans.


Pyruvate carboxylase (PC) is a ligase enzyme that catalyzes the carboxylation of pyruvate to form oxaloacetate (OAA). It is expressed both in prokaryotes and eukaryotes including fungi, bacteria, plants, and animals. In mammals, PC has a crucial role in gluconeogenesis and lipogenesis, in the biosynthesis of neurotransmitters etc. PC deficiency is an inherited disorder that results in lactic acid accumulation in the blood. Three types of PC deficiency have been identified, which are distinguished by the severity of their signs and symptoms.

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