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Pyroxamide

A potent HDAC1 inhibitor
Catalog #: 2189
SKU-Size Size Price Qty
2189-5 5 mg
$70.00
2189-25 25 mg
$310.00
More Sizes Get Quote

Product Details

Alternate Name N1-​hydroxy-​N8-​3-​pyridinyl-​octanediamide
Appearance White to off-white solid
CAS # 382180-17-8
Molecular Formula C₁₃H₁₉N₃O₃
Molecular Weight 265.31
Purity ≥95%
Solubility DMSO (~ 10 mg/ml)
SMILES C1=CC(=CN=C1)NC(=O)CCCCCCC(=O)NO
InChi InChI=1S/C13H19N3O3/c17-12(15-11-6-5-9-14-10-11)7-3-1-2-4-8-13(18)16-19/h5-6,9-10,19H,1-4,7-8H2,(H,15,17)(H,16,18)
InChi Key PTJGLFIIZFVFJV-UHFFFAOYSA-N
PubChem CID 4996
MDL Number MFCD13194970
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Pyroxamide is a potent inhibitor of histone deacetylase 1 (HDAC1) (IC₅₀ = 100 nM). It induces growth suppression and cell death of certain types of cancer cells in culture.


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