Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

PX 12

An irreversible inhibitor of thioredoxin-1 (TRX-1)
Catalog #: 2217
SKU-Size Size Price Qty
2217-5 5 mg
$115.00
2217-25 25 mg
$475.00
More Sizes Get Quote

Product Details

Alternate Name 2-[(1-Methylpropyl)dithio]-1H-imidazole; IV-2
Appearance Beige solid
CAS # 141400-58-0
Molecular Formula C₇H₁₂N₂S₂
Molecular Weight 188.31
Purity ≥98% by HPLC
Solubility DMSO (100 mM)
SMILES CCC(C)SSC1=NC=CN1
InChi InChI=1S/C7H12N2S2/c1-3-6(2)10-11-7-8-4-5-9-7/h4-6H,3H2,1-2H3,(H,8,9)
InChi Key BPBPYQWMFCTCNG-UHFFFAOYSA-N
PubChem CID 219104
MDL Number MFCD18086851
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

PX-12 is an irreversible inhibitor of thioredoxin-1 (TRX-1) (Ki = 31 µM). It decreases the expression of HIF-1α, VEGF and iNOS (IC₅₀ values are 7.2, ~10 and 18.1 μM respectively). Also known to display antitumor activity and inhibits tubulin polymerization in vitro.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.