PTEN Antibody

Catalog #: 3479 | abID:

Product Details

Cat # +Size 3479-100
Size 100 µg
Antibody Target PTEN
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Recombinant human full length PTEN
Accession # P60484
Gene ID 5728
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) antigen affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot, Immunoprecipitation
Application & Usage Western blotting (1-2 µg/ml) and immunoprecipitation (10-20 µg/ml). However, the optimal concentrations should be determined individually.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

PTEN (phosphatase and tensin homologue deleted on chromosome ten) phosphatase is a tumor suppressor gene implicated in a wide variety of human cancers. PTEN encodes the 403 amino acid polypeptide originally described as a dual-specificity protein phosphatase. The main substrates of PTEN are inositol phospholipids generated by the activation of the phosphoinositide 3 kinase (PI3K). PTEN is a major negative regulator of the PI3K/Akt signaling pathway.


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