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An AMPK activator
Catalog #: B2035
SKU-Size Size Price Qty
B2035-5 5 mg
B2035-25 25 mg
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Product Details

Alternate Name 2-Chloro-5-[[5-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]meth-ylene]-4,5-dihydro-4-oxo-2-thiazolyl]amino]benzoic acid
Appearance Brown solid
CAS # 331002-70-1
Molecular Formula C₂₃H₆ClN₃O₆S
Molecular Weight 497.91
Purity ≥98% by HPLC
Solubility DMSO (>40 mg/ml)
SMILES CC1=C(C=C(C(=C1)C2=CC=C(O2)C=C3C(=O)N=C(S3)NC4=CC(=C(C=C4)Cl)C(=O)O)[N+](=O)[O-])C
InChi InChI=1S/C23H16ClN3O6S/c1-11-7-16(18(27(31)32)8-12(11)2)19-6-4-14(33-19)10-20-21(28)26-23(34-20)25-13-3-5-17(24)15(9-13)22(29)30/h3-10H,1-2H3,(H,29,30)(H,25,26,28)/b20-10-
PubChem CID 5753734
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


PT1 is an AMP-activated protein kinase (AMPK) activator. Stimulates AMPK heterotrimer (α1β1γ1) activity (EC = 0.3 μM). Selectively increases the activity of γ1- but not γ3-containing complexes. Directly activates AMPK by antagonizing autoinhibition.

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