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PS-341

A proeasome inhibitor
Catalog #: 1846

In stock

SKU-Size Size Price Qty
1846-1 1 mg
$75.00
1846-5 5 mg
$245.00
More Sizes Get Quote

Product Details

Alternate Name MG-341; ((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid
Appearance White to off-white solid
CAS # 179324-69-7
Molecular Formula C₁₉H₂₅BN₄O₄
Molecular Weight 384.24
Purity ≥99% by HPLC
Solubility DMSO (200mg/ml) or EtOH (200 mg/ml)
SMILES B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
InChi InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1
InChi Key GXJABQQUPOEUTA-RDJZCZTQSA-N
PubChem CID 387447
MDL Number MFCD09056737
Handling Protect from moisture and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A potent (Ki = 0.6 nM), specific and reversible proteasome inhibitor. It inhibits cell proliferation of H460 cells (Human non-small cell lung cancer cell lines) with an IC₅₀ of 0.1 µM.


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