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Protein Disulfide Isomerase (PDI), human recombinant

based on 2 citations in multiple journalsProtein Disulfide Isomerase (PDI), human recombinant24.1 4
Catalyzes disulfide exchange and protein folding
Catalog #: 7601
SKU-Size Size Price Qty
7601-100 100 μg
$195.00
7601-1000 1 mg
$1,100.00
7601-5000 5 mg
$3,950.00
More Sizes Get Quote

Product Details

Alternate Name Protein Disulfide Isomerase, Cellular thyroid hormone-binding protein, Prolyl 4-hydroxylase subunit beta, p55
Gene Symbol PDIA3
Gene ID 2923
Accession # P30101
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and lyophilized with no additives
Molecular Weight 57.1 kDa
Purity by SDS-PAGE ≥95%
Reconstitution Instructions Reconstituted PDI should be stored in working aliquots at -20°C. For long-term storage, it is recommended to add carrier protein (0.1% HAS or BSA).
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Protein disulfide isomerases (PDIs) constitute a family of structurally related enzymes which catalyze disulfide bonds formation, reduction, or isomerization of newly synthesized proteins in the lumen of the endoplasmic reticulum (ER). Human Protein Disulfide Isomerase is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI has been found to have moderate effects (25-fold) on the rate of oxidative folding of proteins in vitro. Recombinant Human PDI produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 508 amino acids and having a molecular mass of 57.1 kDa. The human PDI contains N-terminal 6xHis-tag and is purified by proprietary chromatographic techniques.


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Kothari H et al. (2008) Blood 111: 3295 - 3296.
Pendurthi UR et al. (2007) Blood 110: 3900-3908.
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