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Proteasome Substrate II, Fluorogenic

A sensitive fluorogenic proteasome substrate
Catalog #: B2059
SKU-Size Size Price Qty
B2059-1 1 mg
$75.00
B2059-5 5 mg
$295.00
More Sizes Get Quote

Product Details

Alternate Name Ac-RLR-AMC; Acetyl-Arg-Leu-Arg-7-amido-4-methylcoumarin; Proteasome Substrate
Appearance Lyophilized solid
CAS # 929903-87-7 (free base)
Molecular Formula C₃₀H₄₆N₁₀O₆ .C₂HF₃O₂
Molecular Weight 756.8
Purity ≥97% by HPLC
Solubility DMSO
SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C
InChi InChI=1S/C30H46N10O6/c1-16(2)13-23(40-27(44)21(37-18(4)41)7-5-11-35-29(31)32)28(45)39-22(8-6-12-36-30(33)34)26(43)38-19-9-10-20-17(3)14-25(42)46-24(20)15-19/h9-10,14-16,21-23H,5-8,11-13H2,1-4H3,(H,37,41)(H,38,43)(H,39,45)(H,40,44)(H4,31,32,35)(H4,33,34,36)/t21-,22-,23-/m0/s1
InChi Key DOIHRXFNOWSOMS-VABKMULXSA-N
PubChem CID 131676392
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Proteasome Substrate II is a sensitive fluorogenic substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. It is cleaved exclusively at the amide R-AMC bond to release fluorescent product. Excitation: 380 nm. Emission: 460 nm


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