A substrate of Cytochrome P450 3A4

WARNING: This product can expose you to chemicals including Progesterone, which is [are] known to the State of California to cause cancer.  For more information go to
Catalog #: 2913 | abID:

Product Details

Alternate Name pregn-4-ene-3,20-dione
Appearance Crystalline solid
CAS # 57-83-0
Molecular Formula C₂₁H₃₀O₂
Molecular Weight 314.5
Purity ≥98%
Solubility Acetonitrile or Ethanol or Methanol (~1 mg/ml). Organic solvents should be purged in inert gas. The organic solvent solution can be diluted into aqueous buffers or isotonic saline; sparingly soluble in aqueous solvents directly. Aqueous solutions should n
SMILES C[[email protected]@]12[[email protected]](CC[[email protected]@H]2C(C)=O)([H])[[email protected]]3([H])CCC4=CC(CC[[email protected]]4(C)[[email protected]@]3([H])CC1)=O
InChi InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
PubChem CID 5994
MDL Number MFCD00003658
Handling Do not take internally. Wear gloves and mask when handling! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones. Progesterone is hydroxylated by Cytochrome P450 enzymes like CYP3A4 in the liver.

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