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Oxidative Stress

Oxidative stress is a state when the normal reduced environment of a cell changes due to the accumulation of reactive oxygen species (ROS). These ROS like peroxides, superoxides and free radicals can cause pathological changes in the cell due to DNA damage, oxidation of amino acids, proteins, polyunsaturated fatty acids and enzyme cofactors which subsequently causes cell death due to apoptosis or necrosis. The antioxidant enzymes within the cells like catalase, superoxide dismutase (SOD), lactoperoxidases and glutathione peroxidase inhibit the production of such free radicals and thus protect cells in order to maintain the balance.

Oxidative stress is a hallmark of a number of diseases including Alzheimer's disease, Parkinson's disease, Sickle cell disease, heart failure, myocardial infarction, Schizophrenia, fragile X syndrome, diabetes, cancer, cardiovascular disease and chronic fatigue syndrome. These pathological changes in the cells primarily occur due to DNA damage, oxidation of amino acids, proteins, polyunsaturated fatty acids and enzyme cofactors which subsequently causes cell death due to apoptosis or necrosis.

BioVision has a number of kits for oxidative stress, antibodies, proteins and antioxidants in this behalf to help researchers study and understand the detailed mechanisms on this front.


Annexin V Subcategories

47 Item(s)

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47 Item(s)

per page

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