Lipids Metabolism
An important inflammatory marker, C-RP, is mainly synthesized in the liver though it is also produced in atherosclerotic lesions, the kidney, neurons, and alveolar macrophages. Its physiological role is to bind to phosphatidylcholine expressed on the surface of dead or dying cells (and some bacteria) in order to activate the complement system via the C1Q complex. Hepatic C-RP synthesis is stimulated by the adipokines leptin and IL-6 and down-regulated by adiponectin. C-RP has been shown to impair insulin signaling and contributes to atherothrombosis. Synthesis of fatty acid (de novo) is due to the sole mammalian enzyme, FAS, whose gene expression in adipose tissue is linked to visceral fat accumulation, impaired insulin sensitivity, increased circulating fasting insulin, IL-6, leptin and RBP4. In addition, FAS is highly expressed in most human carcinomas and is associated with poor prognosis in breast and prostate cancer. FAS and fatty acid metabolism in cancer has become a focus for the potential diagnosis and treatment of cancer. S1P is a signaling sphingolipid, also referred to as a bioactive lipid mediator. S1P resides normally on lipoproteins, particularly HDL, and albumin in the circulation. Collective data appears to identify a novel role for sphingolipids in contributing to the prothrombotic and proinflammatory phenotype of the obese adipose tissue currently believed to play a major role in the pathogenesis of obesity-mediated cardiovascular and metabolic disease.
Lipids Metabolism Kits List
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3T3-L1 Differentiation Kit
Catalog #: K579 | Datasheet$265.00 -
Acetate Colorimetric Assay Kit
Catalog #: K658 | Datasheet$425.00 -
Acetoacetate Colorimetric Assay Kit
Catalog #: K650 | Datasheet$645.00 -
Acid Sphingomyelinase Assay Kit II (Colorimetric)
Catalog #: K192 | Datasheet$390.00 -
Acyl-CoA Synthetase Fluorometric Assay Kit
Catalog #: K184 | Datasheet$500.00 -
Aldehyde Dehydrogenase 2 Inhibitor Screening Kit (Fluorometric)
Catalog #: K2011 | Datasheet$495.00 -
Aldehyde Dehydrogenase Activity Colorimetric Assay Kit
Catalog #: K731 | Datasheet$490.00 -
Alkaline Sphingomyelinase Activity Assay Kit (Colorimetric)
Catalog #: K987 | Datasheet$495.00 -
cAMP Phosphodiesterase Activity Assay Kit (Fluorometric)
Catalog #: K2013 | Datasheet$545.00 -
Carboxylesterase Activity Assay Kit (Fluorometric)
Catalog #: K2014 | Datasheet$525.00 -
Cardiolipin Assay Kit (Fluorometric)
Catalog #: K944 | Datasheet$625.00 -
CETP Activity Fluorometric Assay Kit II
Catalog #: K595 | Datasheet$545.00 -
CETP Inhibitor Screening Kit (Fluorometric) II
Catalog #: K594 | Datasheet$575.00 -
Cholesterol Efflux Fluorometric Assay Kit (cell-based)
Catalog #: K582 | Datasheet$845.00 -
Choline Oxidase Activity Assay Kit (Fluorometric)
Catalog #: K2052 | Datasheet$525.00 -
$445.00
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$405.00
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EZClick™ Myristoylated Protein Assay Kit, Red Fluorescence
Catalog #: K177 | Datasheet$425.00 -
$425.00
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$405.00
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$425.00
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$425.00
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EZScreen™ Free Fatty Acid Colorimetric Assay Kit (384-well)
Catalog #: K956 | Datasheet$550.00 -
$505.00
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$530.00
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Free Fatty Acid Quantification Colorimetric/Fluorometric Kit
Catalog #: K612 | Datasheet$515.00 -
Free Glycerol Colorimetric Assay Kit II
Catalog #: K634 | Datasheet$415.00 -
Free Glycerol Colorimetric/Fluorometric Assay Kit
Catalog #: K630 | Datasheet$440.00 -
Glucosylceramidase Activity Assay Kit (Fluorometric)
Catalog #: K2003 | Datasheet$515.00 -
Glycerol Cell-Based Assay Kit
Catalog #: K977 | Datasheet$405.00 -
Glycerol-3-Phosphate (G3P) Colorimetric Assay Kit
Catalog #: K641 | Datasheet$455.00 -
Glycerol-3-Phosphate Dehydrogenase Activity Colorimetric Assay Kit
Catalog #: K640 | Datasheet$535.00 -
Glycerophosphorylcholine Assay Kit (Colorimetric/Fluorometric)
Catalog #: K433 | Datasheet$475.00 -
HDL and LDL/VLDL Quantification Colorimetric/Fluorometric Kit
Catalog #: K613 | Datasheet$545.00 -
HDL Uptake Assay Kit (Fluorometric)
Catalog #: K586 | Datasheet$755.00 -
Hepatic Steatosis Assay Kit
Catalog #: K584 | Datasheet$415.00 -
HMG-CoA Reductase Activity/Inhibitor Screening Kit (Colorimetric)
Catalog #: K588 | Datasheet$625.00 -
Hydroxy Acid Oxidase Activity Assay Kit (Fluorometric)
Catalog #: K2010 | Datasheet$445.00 -
Lipase Activity Colorimetric Assay Kit
Catalog #: K722 | Datasheet$425.00 -
Lipase Activity Fluorometric Assay Kit III
Catalog #: K724 | Datasheet$435.00 -
Lipid (Oil Red O) staining Kit
Catalog #: K580 | Datasheet$370.00 -
Lipid Extraction Kit (Chloroform Free)
Catalog #: K216 | Datasheet$285.00 -
Lipid Peroxidation Colorimetric Assay Kit
Catalog #: K454 | Datasheet$475.00 -
Lipolysis (3T3-L1) Colorimetric Assay Kit
Catalog #: K577 | Datasheet$460.00 -
Lipolysis (Adipocyte) Colorimetric/Fluorometric Assay Kit
Catalog #: K581 | Datasheet$545.00 -
Lipoprotein Lipase Activity Fluorometric Assay Kit
Catalog #: K721 | Datasheet$450.00 -
PAF Acetylhydrolase (PAF-AH) Inhibitor Screening Kit (Colorimetric)
Catalog #: K766 | Datasheet$355.00 -
PAF Acetylhydrolase Activity Assay Kit (Colorimetric)
Catalog #: K765 | Datasheet$365.00 -
Phosphatidylcholine Colorimetric/Fluorometric Assay Kit
Catalog #: K576 | Datasheet$405.00 -
Phospholipase A2 Activity Assay Kit (Fluorometric)
Catalog #: K400 | Datasheet$475.00