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Fluorescent Exosome Standard

Exosomes are small endosome derived lipid nanoparticles (50-120 nm) actively secreted by exocytosis by most living cells. Exosome release occurs either constitutively or upon induction, under both normal and pathological conditions, in a dynamic, regulated and functionally relevant manner. Both the amount and molecular composition of released exosomes depend on the state of a parent cell. Exosomes have been isolated from diverse cell lines (hematopoietic cells, tumor lines, primary cultures, and virus infected cells) as well as from biological fluids in particular blood (e.g. serum and plasma from cancer patients) and other body fluids (broncho alveolar lavage fluid, pleural effusions, synovial fluid, urine, amniotic fluid, semen, saliva etc).

BioVision offers Fluorescent Exosome Standards for EV tracking in fluorescence microscopy experiments. Fluorescent exosomes are labeled with green dye, which provides a stable fluorescent labeling and are suitable for different applications providing a long-lasting well visible signal. Fluorescent exosomes are quantified for overall protein content and particle number and validated by Nanoparticles Tracking Analysis (NTA, NanoSight). One vial contains 100 µg of purified liquid exosome solution (measured as total protein content; number of particles in 100 µg: >1x1010). The excitation maximum of fluorescent exosome standards is 500 nm-650 nm and emission maximum is 510 nm-665 nm.

1. ExoStd™ Fluorescent Exosome Standards from Human Biological Fluids:
Purified exosomes from Human Plasma, Serum and Urine (pools of healthy donors)

2. ExoStd™ Fluorescent Exosome Standards from Cell Culture Supernatants:
Purified exosomes from supernatants of a wide list of Cell Culture Media

Fluorescent Exosome Standards Subcategories