You have no items in your shopping cart.
CDK Inhibitors
Uncontrolled cellular proliferation mediated by the dysregulation of cell-cycle machinery and activation of cyclin-dependent kinases (CDKs) is the hallmark of cancer. Agents targeting CDKs have been considered as promising therapeutic targets in cancer treatment. Although the first-generation pan-CDK inhibitors failed in clinical trials because of their adverse events and low efficacy, most recently, a new generation of selective CDK4/6 inhibitors, including Ribociclib, Abemaciclib and Palbociclib, has shown potent efficacy with tolerable safety in preclinical and clinical studies. Recent approval of Palbociclib (Ibrance®) by the U.S. Food and Drug Administration (FDA) for the treatment of ER-positive and HER2-negative breast cancer demonstrates that CDK inhibitors with high selectivity profiles can have clinical utility for therapy based on individual tumor genetics. BioVision is proud to offer >25 potent and selective CDK inhibitors including Palbociclib (PD0332991), Abemaciclib (LY-2835219), Dinaciclib, and Ribociclib for research.
-
(R)-Perharidine-1
Catalog #: 2615 | DatasheetStarting at: $105.00
-
10Z-Hymenialdisine
Catalog #: 2212 | DatasheetStarting at: $175.00
-
Starting at: $85.00
-
Alsterpaullone
Catalog #: 1897 | DatasheetStarting at: $95.00
-
Starting at: $125.00
-
Aminopurvalanol A
Catalog #: 2205 | DatasheetStarting at: $60.00
-
Arcyriaflavin A
Catalog #: B2902 | DatasheetStarting at: $95.00
-
AT-7519 hydrochloride
Catalog #: 2816 | DatasheetStarting at: $95.00
-
Atuveciclib
Catalog #: B2440 | DatasheetStarting at: $115.00
-
Starting at: $115.00
-
Starting at: $135.00
-
BS-181 dihydrochloride
Catalog #: B2180 | DatasheetStarting at: $115.00
-
Butyrolactone I
Catalog #: 1690 | Datasheet$130.00 -
CCT-251921
Catalog #: B2502 | DatasheetStarting at: $85.00
-
Cdk4 Inhibitor
Catalog #: B2928 | DatasheetStarting at: $145.00
-
Cdk9 Inhibitor II
Catalog #: B2903 | DatasheetStarting at: $85.00
-
Starting at: $95.00
-
Dinaciclib
Catalog #: 9537 | DatasheetStarting at: $125.00
-
EZSolution™ AZD-5438
Catalog #: B2624 | Datasheet$125.00 -
Flavopiridol
Catalog #: 2090 | DatasheetStarting at: $90.00
-
Kenpaullone
Catalog #: 1904 | Datasheet$80.00 -
LY-2835219
Catalog #: B1039 | DatasheetStarting at: $125.00
-
MSC-2530818
Catalog #: B1975 | DatasheetStarting at: $95.00
-
Starting at: $145.00
-
Starting at: $65.00
-
Starting at: $145.00
-
PD-0332991
Catalog #: 2843 | DatasheetStarting at: $95.00
-
PD-0332991 isethionate
Catalog #: 9480 | DatasheetStarting at: $115.00
-
RGB-286638, free base
Catalog #: 2886 | DatasheetStarting at: $165.00
-
Ribociclib (LEE011)
Catalog #: 9481 | DatasheetStarting at: $95.00
-
Riviciclib hydrochloride
Catalog #: B2567 | DatasheetStarting at: $85.00
-
Starting at: $70.00
-
Roscovitine
Catalog #: 1950 | DatasheetStarting at: $60.00
-
Starting at: $145.00
-
Starting at: $100.00
-
THZ1 (Free base)
Catalog #: 9664 | DatasheetStarting at: $225.00
-
THZ1 hydrochloride
Catalog #: 9544 | DatasheetStarting at: $235.00
-
WAY-265497
Catalog #: B2936 | DatasheetStarting at: $155.00
