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Citrullination Research

Citrullination is the conversion of the amino acid arginine into citrulline in target proteins by peptidylarginine deiminases (PADs). Citrulline is not one of the 20 standard amino acids, but rather the result of a post-translational modification. Citrullination of proteins is important for maintaining normal physiological functions, including gene regulation through histone modification, immune responses, etc. However, increased citrullination has been associated with immune pathological conditions and neurological disorders such as rheumatoid arthritis, multiple sclerosis, and Alzheimer’s disease. BioVision is proud to offer a comprehensive portfolio of assay kits, proteins and enzymes, antibodies, and biochemicals to facilitate citrullination research.

 


Citrullination Categories