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PI 3-Kinase Inhibitors
Phosphatidylinositol 3-kinases (PI3Ks) are lipid kinases that play central role in regulation of cell cycle, apoptosis, DNA repair, senescence, angiogenesis, cellular metabolism, and motility. Dysregulated PI3K pathway signaling occurs in one-third of human tumors. The frequent activation of the PI3K pathway in cancer and its crucial role in cell growth and survival has made it an attractive therapeutic target. In the last few years, several classes of potent and selective small molecule PI3K inhibitors have been developed as anticancer drugs. Idelalisib was the first PI3K inhibitor approved by the US FDA for the treatment of relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma and follicular lymphoma. Copanlisib was later approved for relapsed follicular lymphoma in patients who have received at least two prior systemic therapies. Numerous other PI3K inhibitors are currently in development targeting various combinations of PI3K isoforms. BioVision is proud to offer ~60 PI3K inhibitors for research.
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Starting at: $235.00
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Starting at: $100.00
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Starting at: $115.00
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Starting at: $115.00
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Starting at: $125.00
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Starting at: $60.00
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Starting at: $95.00
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Starting at: $145.00
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Starting at: $165.00
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Starting at: $100.00
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Starting at: $125.00
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BAY 80-6946
Catalog #: B1267 | DatasheetStarting at: $175.00
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BEZ235 (NVP-BEZ235)
Catalog #: 1626 | DatasheetStarting at: $140.00
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CAL-101 (GS-1101)
Catalog #: 2613 | DatasheetStarting at: $75.00
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Starting at: $65.00
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Starting at: $100.00
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Starting at: $100.00
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Starting at: $100.00
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Starting at: $115.00
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DiscoveryPak™ PI 3-Kinase Inhibitor Set
Catalog #: K856 | Datasheet$435.00 -
EZSolution™ LY294002
Catalog #: 1747 | Datasheet$85.00 -
Starting at: $125.00
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Starting at: $114.00
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Starting at: $150.00
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GSK-1059615
Catalog #: 9450 | DatasheetStarting at: $115.00
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GSK-2126458
Catalog #: 1961 | DatasheetStarting at: $100.00
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GSK2292767
Catalog #: B1660 | DatasheetStarting at: $85.00
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GSK2636771
Catalog #: 2793 | DatasheetStarting at: $125.00
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$205.00
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Starting at: $125.00
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Starting at: $115.00
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Leniolisib
Catalog #: B2435 | DatasheetStarting at: $155.00
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Starting at: $85.00
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Starting at: $125.00
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NVP-BKM120
Catalog #: 2619 | DatasheetStarting at: $85.00
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PathwayReady™ PI3-K/Akt/mTOR Signaling Inhibitor Panel
Catalog #: K857 | Datasheet$935.00 -
Starting at: $95.00
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Starting at: $100.00
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PI3-Kɣ Inhibitor, AS-605240
Catalog #: 1780 | DatasheetStarting at: $75.00
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PI3K-α Inhibitor
Catalog #: B1869 | DatasheetStarting at: $145.00
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Starting at: $175.00
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Starting at: $115.00
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Starting at: $100.00
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Starting at: $115.00
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Starting at: $70.00
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Starting at: $85.00
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Starting at: $70.00
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SAR-260301
Catalog #: B1263 | DatasheetStarting at: $145.00
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Serabelisib
Catalog #: B1930 | DatasheetStarting at: $125.00
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Starting at: $85.00
