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Inflammasome Inhibitors
The inflammasomes are innate immune system sensors that control the activation of caspase-1 and induce inflammation in response to infectious microbes and molecules originating from host proteins, leading to the release of pro-inflammatory cytokines, Il-1β and IL-18. The best characterized inflammasome is NLRP3, so-called because the NLRP3 protein in the complex belongs to the family of nucleotide-binding and oligomerization domain-like receptors (NLRs) and is also known as “pyrin domain-containing protein 3”. The NLRP3 inflammasome is associated with onset and progression of various diseases such as metabolic disorders, multiple sclerosis, inflammatory bowel disease, cryopyrin-associated periodic fever syndrome, as well as other auto-immune and auto-inflammatory diseases. BioVision is proud to offer several structurally diverse inflammasome inhibitors for research.
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Starting at: $185.00
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BAY 11-7082
Catalog #: 1867 | DatasheetStarting at: $120.00
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Caspase-1 Inhibitor Z-YVAD-FMK
Catalog #: 1012 | DatasheetStarting at: $135.00
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Caspase-Family Inhibitor Z-VAD-FMK
Catalog #: 1010 | DatasheetStarting at: $135.00
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Glibenclamide
Catalog #: 1878 | DatasheetStarting at: $70.00
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Isoliquiritigenin
Catalog #: 2528 | DatasheetStarting at: $125.00
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MCC950 (Free base)
Catalog #: B1031 | DatasheetStarting at: $95.00
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MCC950 sodium
Catalog #: 9686 | DatasheetStarting at: $115.00
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Starting at: $75.00
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Parthenolide
Catalog #: 1868 | DatasheetStarting at: $70.00
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Resveratrol
Catalog #: 1758 | DatasheetStarting at: $70.00
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Starting at: $115.00
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Starting at: $215.00
