Biosimilar Antibodies
What exactly are Biosimilars and why are they so important?
According to the US Food and Drug Administration (FDA) definition, Biosimilars are biological products such as drugs, proteins, peptides and monoclonal antibodies that are very similar in safety, purity and efficacy to that of US FDA approved original innovative medicinal products. Biosimilars have the same active biological component as the original medicinal product. However, they are different in terms of inactive components and methods of production. In contrast to original medicinal product, Biosimilars are allowed to have only minor changes in their inactive components, which involves extensive analytical studies. This includes the study of structure and function of biological product, determination of toxicity, and pharmacological studies involving the assessment of pharmacokinetic and pharmacodynamic profile.
BioVision is pleased to offer research grade biosimilars for your research needs. These biosimilar antibodies can be used as controls for preclinical lead identification as well as the development of novel assays and to explore new avenues in biological research.
Are Biosimilars different from Generic drugs?
Biosimilars and Generic drugs are different brand names for the same original innovative medicinal product. Although both are aimed at providing affordable treatment options for patients, their development and approval process avoid replicating the lengthy and expensive process of clinical trials. Generics are usually small molecule drugs that are prepared through a series of chemical reactions in such a way that they will give exact identical copies of original medicinal product. Biosimilars are large biological molecules that are produced by living cells and involves several steps of cloning, cell line maintenance and expansion, product isolation, purification and characterisation. Due to constant changes in living cells, it is very difficult to produce identical copies of Biosimilars
What are Biosimilar Monoclonal Antibodies?
Biosimilar Monoclonal Antibodies are large complex proteins that are produced by living organisms. These antibodies help the immune system to fight diseases such as cancer, haematologic and autoimmune diseases by way of identification and neutralization of foreign microorganisms such as virus and bacteria. Due to expiration of patents of some of the blockbuster drugs, Biosimilar Monoclonal Antibodies are becoming increasingly popular in recent years. They are predicted to be the global leaders in the field of biopharmaceuticals. Hence, to support the customer’s Biosimilar-based research programs, BioVision offers Biosimilar Monoclonal Antibodies that have wide variety of research applications.
Features & Benefits
• Research-grade antibodies prepared in PBS
• Low endotoxicity
• Highly pure (˃98%)
• Used for drug potency assay development and identification of pre-clinical leads
• Bulk quotes available
