Acetylation-specific Antibodies
BioVision is proud to offer a variety of antibodies to detect acetylated proteins.
Acetylation is a type of post-translational modification of the protein, which involves the addition of an acetyl group (donated by acetyl coenzyme A) on either the N-terminal amino acid residue or ε-amino acid group on lysine residues. N-terminal acetylation occurs in about 80-90% of the proteins, irreversibly catalyzed by N-terminal acetyltransferases (NATs). Although the physiological role is unknown, N-terminal acetylation has been demonstrated in studies to affect the folding of proteins, localization, and interaction with other proteins. On the other hand, Lysine acetylation is a reversible modification that is catalyzed by Lysine acetyltransferases and occurs in histone proteins, transcription factors, cytoskeletal proteins, and chaperone proteins. Lysine specific acetylation is known to regulate several functions such as gene expression, metabolism, and other key cellular pathways. Due to its versatile functions, protein acetylation is associated with several diseases such as cancer, neurodegenerative diseases, and diabetes. BioVision offers a number of antibodies that detect protein acetylation to aid researchers in their acetylation studies.
Features & Benefits
• High quality Acetyl specific antibodies
• Affinity purified
• Available in monoclonal and polyclonal formats
• Validated in multiple research applications such as Western blot, CHIP, IHC, ICC etc.
