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Acetylation-specific Antibodies

BioVision is proud to offer a variety of antibodies to detect acetylated proteins.

Acetylation is a type of post-translational modification of the protein, which involves the addition of an acetyl group (donated by acetyl coenzyme A) on either the N-terminal amino acid residue or ε-amino acid group on lysine residues. N-terminal acetylation occurs in about 80-90% of the proteins, irreversibly catalyzed by N-terminal acetyltransferases (NATs). Although the physiological role is unknown, N-terminal acetylation has been demonstrated in studies to affect the folding of proteins, localization, and interaction with other proteins. On the other hand, Lysine acetylation is a reversible modification that is catalyzed by Lysine acetyltransferases and occurs in histone proteins, transcription factors, cytoskeletal proteins, and chaperone proteins. Lysine specific acetylation is known to regulate several functions such as gene expression, metabolism, and other key cellular pathways. Due to its versatile functions, protein acetylation is associated with several diseases such as cancer, neurodegenerative diseases, and diabetes. BioVision offers a number of antibodies that detect protein acetylation to aid researchers in their acetylation studies.

 

 

Features & Benefits

• High quality Acetyl specific antibodies
• Affinity purified
• Available in monoclonal and polyclonal formats
• Validated in multiple research applications such as Western blot, CHIP, IHC, ICC etc.

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BioVision, Inc.

BioVision, Inc., is a privately held Life Science company headquartered in the beautiful San Francisco Bay Area.

BioVision develops and offers a wide variety of products including assay kits, antibodies, recombinant proteins & enzymes, and other innovative research tools for studying Apoptosis, Metabolism, Cell Proliferation, Cellular Stress, Cell Damage and Repair, Diabetes, Obesity and Metabolic Syndrome, Stem Cell Biology, Gene Regulation, Signal Transduction, etc. BioVision's products are currently being sold in more than 60 countries worldwide.

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155 S Milpitas Blvd. Milpitas, CA 95035.
Tel: 408.493.1800
Fax: 408.493.1801
Toll Free: 800.891.9699 (US Only)
Tech Support: [email protected]
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All products are For Research Use Only. Not for use in diagnostic or therapeutic uses. Do not use in humans.
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