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K101 :: Annexin V-FITC Apoptosis Assay Kit
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Chen, Ping et al. (2016) Neddylation Inhibition Activates the Extrinsic Apoptosis Pathway through ATF4–CHOP–DR5 Axis in Human Esophageal Cancer Cells, Clin Cancer Res. 2016 Aug 15;22(16):4145-57.
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Hayashi, H. et. al. Characterization of dsRNA-induced pancreatitis model reveals the regulatory role of IFN regulatory factor 2 (Irf2) in trypsinogen5 gene transcription. PNAS, Nov 2011; 108: 18766 - 18771.
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Herrmann, A. et al. Targeting Stat3 in the Myeloid Compartment Drastically Improves the In vivo Antitumor Functions of Adoptively Transferred T Cells
Hidemi Takahashi et al., Induction of rapid apoptosis for class I MHC molecule-restricted CD8+ HIV-1 gp160-specific murine activated CTLs by free antigenic peptide in vivo. Int. Immunol., Jan 2013; 25: 11 - 24.
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Hiroyuki Monma et al., The HSP70 and Autophagy Inhibitor Pifithrin-μ Enhances the Antitumor Effects of TRAIL on Human Pancreatic Cancer. Mol. Cancer Ther., Apr 2013; 12: 341 - 351.
Ho et al., Ferruginol Inhibits Non–Small Cell Lung Cancer Growth by Inducing Caspase-Associated Apoptosis. Integr Cancer Ther, Jan 2015; 14: 86 - 97.
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Hu, Ying et al. (2017) Splicing factor hnRNPA2B1 contributes to tumorigenic potential of breast cancer cells through STAT3 and ERK1/2 signaling pathway, Tumour Biol. 2017 Mar;39(3):1010428317694318.
Huang Li et al., Endoplasmic Reticulum Stress Regulates Rat Mandibular Cartilage Thinning under Compressive Mechanical Stress. J. Biol. Chem., Jun 2013; 288: 18172 - 18183.
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Huanzi Dai et al., TSSC3 overexpression associates with growth inhibition, apoptosis induction and enhances chemotherapeutic effects in human osteosarcoma, Carcinogenesis, Jan 2012; 33: 30 - 40.
Huck, J. et al. MLN8054, an Inhibitor or Aurora A Kinase Induces Senescence in Human Tumor Cells Both In Vitro and In Vivo. Mol. Cancer Res. 2010 8: 373-384.
Hurley et al., Alpha-1 Antitrypsin Augmentation Therapy Corrects Accelerated Neutrophil Apoptosis in Deficient Individuals. J. Immunol., Oct 2014; 193: 3978 - 3991.
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Itamochi, H. et. al. Inhibiting the mTOR Pathway Synergistically Enhances Cytotoxicity in Ovarian Cancer Cells Induced by Etoposide through Upregulation of c-Jun. Clin. Cancer Res., Jul 2011; 17: 4742 - 4750.
Ito et al., Human NAT10 Is an ATP-dependent RNA Acetyltransferase Responsible for N4-Acetylcytidine Formation in 18 S Ribosomal RNA (rRNA). J. Biol. Chem., Dec 2014; 289: 35724 - 35730.
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K102 :: Annexin V-Cy3 Apoptosis Assay Kit
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K103 :: Annexin V-Cy5 Apoptosis Assay Kit
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K104 :: Annexin V-EGFP Apoptosis Assay Kit
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K105 :: Caspase-3 Fluorometric Assay Kit
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K106 :: Caspase-3 Colorimetric Assay Kit
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K107 :: Caspase-Family Inhibitor Set
Wang SH et al. (2007) Endocrinology 148: 4844-4852

K108 :: Caspase-Family Inhibitor Set II
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K109 :: Annexin V-Biotin Apoptosis Kit
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K110 :: Caspase-1 Fluorometric Assay Kit
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K111 :: Caspase-1 Colorimetric Assay Kit
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K112 :: Caspase-8 Fluorometric Assay Kit
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K113 :: Caspase-8 Colorimetric Assay Kit
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Moriceau S et al (2009) J. Immunol.; 182: 7254 - 7263.
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Nie et al., Involvement of mitochondrial pathway in benzo[a]pyrene-induced neuron apoptosis.
Human and Experimental Toxicology, Jul 2013; 10.1177/0960327113493301.
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Wang W et al. (2007) Clin. Cancer Res. 13: 4891-4899.
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K114 :: Caspase-6 Fluorometric Assay Kit
Chen T-H et al (2008) Clin. Cancer Res. 14: 4250- 4258.
Coletti, D., et al. (2002) EMBO J. 21:631-642.
Deane, A, Jennifer., et al. (2004) J. Immunol. 172:6615-6625.

K115 :: Caspase-6 Colorimetric Assay Kit
Chen T-H et al (2008) Clin. Cancer Res. 14: 4250- 4258.
Doostzadeh J., et al. (2000) J. Biol. Chem. 275:25336-25341.
Jiang, J.D., et al. (2002) Cancer Res. 62:6080-6088.
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Nabatchian F et al., (2017) New 6(17)-epoxylathyrane diterpene: aellinane from Euphorbia aellenii induces apoptosis via mitochondrial pathway in ovarian cancer cell line, Tox Mech Methods, 2017, June-27: epub

K116 :: Caspase-2 Fluorometric Assay Kit
Chan, K. et al. Goniothalamin Induces Coronary Artery Smooth Muscle Cells Apoptosis: The p53-Dependent Caspase-2 Activation Pathway. Toxicol. Sci., 2010; 116: 533-548.
Li J., et al. (2002) J. Biol. Chem. 277:49504-49510.
Sapet C. et al. (2006) Blood 108: 1868-1876.

K117 :: Caspase-2 Colorimetric Assay Kit
Chen T-H et al (2008) Clin. Cancer Res. 14: 4250- 4258.
Erika Segear Johnson et al., Metabolomic Profiling Reveals a Role for Caspase-2 in Lipoapoptosis. J. Biol. Chem., May 2013; 288: 14463 - 14475.
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K118 :: Caspase-9 Fluorometric Caspase Assay Kit
Andrea Callegari, et. al. Gain and Loss of Function for Glutathione Synthesis: Impact on Advanced Atherosclerosis in Apolipoprotein E–Deficient Mice. Arterioscler Thromb Vasc Biol, Nov 2011; 31: 2473 - 2482.
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Maity P et al (2008) J. Biol. Chem. 283: 14391.
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Sangeeta Maity et al., Hyperthyroidism causes cardiac dysfunction by mitochondrial impairment and energy depletion. J. Endocrinol., Apr 2013; 217: 215 - 228.
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K119 :: Caspase-9 Colorimetric Assay Kit
Alajiz N et al (2008) Clin. Cancer Res. 14: 4891 - 4897.
Anderson, E. J. et. al. Increased propensity for cell death in diabetic human heart is mediated by mitochondrial-dependent pathways. Am J Physiol Heart Circ Physiol, Jan 2011; 300: H118 - H124.
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Bindu, S. et. al. Translocation of Heme Oxygenase-1 to Mitochondria Is a Novel Cytoprotective Mechanism against Non-steroidal Anti-inflammatory Drug-induced Mitochondrial Oxidative Stress, Apoptosis, and Gastric Mucosal Injury. J. Biol. Chem., Nov 2011; 286: 39387 - 39402.
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Chun-Chen Chen et al., Coenzyme Q10 Rescues Ethanol-induced Corneal Fibroblast Apoptosis through the Inhibition of Caspase-2 Activation. J. Biol. Chem., Apr 2013; 288: 11689 - 11704.
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Maity P et al (2009) J. Biol. Chem.; 284: 3058-3068
Maity P wt al (2008) J. Biol. Chem. 283: 14391.
Maity, B. et. al. Regulator of G Protein Signaling 6 (RGS6) Induces Apoptosis via a Mitochondrial-dependent Pathway Not Involving Its GTPase-activating Protein Activity. J. Biol. Chem., Jan 2011; 286: 1409 - 1419.
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K120 :: Quick Apoptotic DNA Ladder Detection Kit
Cantaluppi V et al (2009) J. Am. Soc. Nephrol. 19: 1904-1918.
Kang SG et al. (2007) J. Biol. Chem. 282: 6090-6097.
Li, Y.P. and M.B. Raid. (2000) Am J Physiol Regul Integr Comp Physiol 279:1165-1170.
Li, C.Q., et al. (2002) PNAS 99:10364-10369.
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Mai, W., et al. (2005) Mol. Biol. Cell. 16: 4398-4409.
Nasu K et al. (2007) Am. J. Physiol. Endocrinol. Mrtab. 293: E16-E23.
Nishida, M., et al. (2005) Mol. Hum. Reprod. 11: 29-34.
Nishida M. et al. (2006) Hum Reprod. 10.1093/humrep/del270.
Papineni S et al. (2008) Mol. Pharmacol. 73: 553-565.
Saito, S. (2005) Am J Lung Ccell Mol Physiol 289: L400-L406.
Sordet O et al (2008) J. Biol. Chem. 283: 23200 - 23208.
Vertrees R. A., et al. (2004) Chest 125: 1472-1482.
Wei Y. et al. (2006) Am. J. Physiol. Endocrinol. Metab. 291: E275-E281.
Wang L et al (2008) Cancer Res. 68: 4377-4383.

K122 :: Caspase-5 Fluorometric Assay Kit
Coletti, D., et al. (2002) EMBO J. 21:631-642.

K123 :: Caspase-5 Colorimetric Assay Kit
Chen T-H et al (2008) Clin. Cancer Res. 14: 4250- 4258.
Bian. Z-M et. al. Expression and Functional Roles of Caspase-5 in Inflammatory Responses of Human Retinal Pigment Epithelial Cells. Invest. Ophthalmol. Vis. Sci., Nov 2011; 52: 8646 - 8656.

K125 :: Caspase-10 Colorimetric Assay Kit
Chen T-H et al (2008) Clin. Cancer Res. 14: 4250- 4258.

K126 :: Caspase-4 Fluorometric Assay Kit
Akamatsu K et al (2009) Anticancer Res; 29: 2195-2204.

K127 :: Caspase-4 Colorimetric Assay Kit
Chen T-H et al (2008) Clin. Cancer Res. 14: 4250- 4258.
Zhang et al., Enhanced endoplasmic reticulum SERCA activity by overexpression of hepatic stimulator substance gene prevents hepatic cells from ER stress-induced apoptosis. Am J Physiol Cell Physiol, Feb 2014; 306: C279 - C290.

K128 :: Annexin V-PE Apoptosis Detection Kit
Banerjee P et al. (2007) J. Virol. 81: 1690-1700, 9707-9717.
Chen C-L et al (2008) Blood, 111: 4365 - 4374.
Chen Q et al (2008) Blood 111: 4690-4699.
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Horton HM et al (2008) Cancer Res., Oct 2008; 68: 8049 - 8057.
Julia L. Cook, et. al. Expression of a naturally occurring angiotensin AT1 receptor cleavage fragment elicits caspase-activation and apoptosis. Am J Physiol Cell Physiol, Nov 2011; 301: C1175 - C1185.
Kang, W. et. al. Yes-Associated Protein 1 Exhibits Oncogenic Property in Gastric Cancer and Its Nuclear Accumulation Associates with Poor Prognosis. Clin. Cancer Res., Apr 2011; 17: 2130 - 2139.
Kuang S. et. al. Aberrant DNA methylation and epigenetic inactivation of Eph receptor tyrosine kinases and ephrin ligands in acute lymphoblastic leukemia Blood, Mar 2010; 115: 2412 - 2419.
Kusakabe, M. et. al. c-Maf plays a crucial role for the definitive erythropoiesis that accompanies erythroblastic island formation in the fetal liver. Blood, Aug 2011; 118: 1374 - 1385.
Li et al., Phosphorylation of Merkel Cell Polyomavirus Large Tumor Antigen at Serine 816 by ATM Kinase Induces Apoptosis in Host Cells. J. Biol. Chem., Jan 2015; 290: 1874 - 1884.
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Yue Z et al (2008) J. Cell Biol.; 183: 279 - 296.
Zhao T et al (2008) Blood; 10.1182/blood-2008-06-161729.

K129 :: Annexin V-PE-Cy5 Apoptosis Detection
Kakhlon O et al (2008) Blood; 112: 5219 - 5227.
Reininger, A.J., et al. (2006) Blood 10.1182/blood-2005-02-0618.
Yue Z et al (2008) J. Cell Biol.; 183: 279 - 296.

K130 :: Enhanced Apoptotic DNA Ladder Detection Kit
Ito M. et al. (2006) J. Immunol. 176: 5637-5643.
Kang SG et al. (2007) J. Biol. Chem. 282: 6090-6097.
Nasu K. et al. (2006) Am J. Physiol. Endocrinol. Metab. 10.1152/ajpendo.00135.2006.
Papineni S et al. (2008) Mol. Pharmacol. 73: 553 - 565.
Wang L et al (2008) Cancer Res. 68: 4377-4383.
Wong, C.K. et al.  Thymic Stromal Lymphopoietin Induces Chemotactic and Prosurvival Effects in Eosinophils: Implications in Allergic Inflammation.Am. J. Respir. Cell Mol. Biol., Sep 2010; 43: 305 - 315.
WOO HYUN PAIK et al., Chemosensitivity Induced by Down-regulation of MicroRNA-21 in Gemcitabine-resistant Pancreatic Cancer Cells by Indole-3-Carbinol. Anticancer Res, Apr 2013; 33: 1473 - 1481.

K132 :: Caspase Colorimetric Substrate Set
Doostzadeh-Cizero, J., et al. (2002) J. Biol. Chem. 275:25336-25341.
Ishimaru N et al (2008) J. Exp. Med.; 205: 2915 - 2927.

K134-9-25 :: Caspase Family Colorimetric Substrate Set II
Ishimaru, N. et al. (2006) Mol. Cell Biol. 26: 2924-1935.
Ishimaru N et al (2008) J. Exp. Med.; 205: 2915 - 2927.
Kanan, Y. et al. (2007) Invest. Opyhalmol. Vis. Sci. 48: 40 - 51.
Rajala A et al (2008) J. Biol. Chem. 10.1074/jbc.M802374200.
•Won S. et al. (2007) J. Virol. 10.1128/JVI01238-07.

K135-7-25 :: Caspase Fluorometric Set Plus
Wang L. et al. (2006) Am. J. Physiol. Lung Cell Mol. Physiol. 290: L695-L702.

K136-7-25 :: Caspase Family Colorimetric Substrate Plus
Ishimaru N et al (2008) J. Exp. Med.; 205: 2915 - 2927.
Wang L. et al. (2006) Am. J. Physiol. Lung Cell Mol. Physiol. 290: L695-L702.
Won S. et al. (2007) J. Virol. 10.1128/JVI01238-07.

K137-9-25 :: Caspase Fluorometric Substrate Set II Plus
Xia Q. et al. (2007) Experimental Biology and Medicine 232: 52-57.

K138-9-25 :: Caspase Colorimetric Substrate Set II Plus
Kanan, Y. et al. (2007) Invest. Opyhalmol. Vis. Sci. 48: 40 - 51.
Liu J et al (2008) Infect. Immun. 76: 3784-3792.

K139 :: Caspase-12 Fluorometric Kit
Baumgartner H et al. (2007) Am. J. Physiol. Gastrointest. Liver Physiol. 10.1152/ajpgi.00103.2007.
Daniel R. Dietrich et al., L-BMAA Induced ER Stress and Enhanced Caspase 12 Cleavage in Human Neuroblastoma SH-SY5Y Cells at Low Nonexcitotoxic Concentrations. Toxicol. Sci., Jan 2013; 131: 217 - 224.
Fu HY et al (2008) Cardiovasc. Res. 10.1093/cvr/cvn128.
Ihara, Y., et al. (2006) Am J Physiol Cell Physiol. 290: C208-C221.
Kikuchi H. et al. (2006) PNAS 103: 6025-6030.
Kulkarni MM et al (2009) J. Biol. Chem.; 284: 15496 - 15504.
Li, X. M. et al., (2017) Isorhynchophylline Attenuates MPP+-Induced Apoptosis Through Endoplasmic Reticulum Stress-and Mitochondria-Dependent Pathways in PC12 Cells: Involvement of Antioxidant Activity , NeuroMolecular Medicine, Aug.2017, 1-13
Liu, Y. et al., (2017) N‑acetylcysteine induces apoptosis via the mitochondria‑dependent pathway but not via endoplasmic reticulum stress in H9c2 cells, Molecular Medicine Reports, Sep.2017, 6626-6633
Neekhra A et al. (2007) Invest. Opthalmol Vis. Sci. 48: 1362-1367.
Peyrou M et al. (2007) Toxicol. Sci. 99: 346-353.
Trisciuoglio D et al (2008) J Natl Cancer Inst 100: 1233-1246.
Zhou, H., et al. (2005) Mol. Pharmacol. 68: 690-700.

K140 :: Cathepsin B Activity Assay Kit
Ha S-D et al (2008) J. Immunol. 181: 690-697.
Irani, D. N. et al Cleavage of Cystatin C in the Cerebrospinal Fluid of Patients with Multiple Sclerosis Ann Neurol Feb 2006
Liu et al., Autophagy-Lysosome Pathway in Renal Tubular Epithelial Cells Is Disrupted by Advanced Glycation End Products in Diabetic Nephropathy.   J. Biol. Chem., Aug 2015; 290: 20499 - 20510.
Liu et al., Urinary proteins induce lysosomal membrane permeabilization and lysosomal dysfunction in renal tubular epithelial cells. Am J Physiol Renal Physiol, Mar 2015; 308: F639 - F649.
Schmidt, S. et. al. Kindlin-3–mediated signaling from multiple integrin classes is required for osteoclast-mediated bone resorption. J. Cell Biol., Mar 2011; 192: 883 - 897.
Siqi Liu et al., Matrine, a novel autophagy inhibitor, blocks trafficking and the proteolytic activation of lysosomal proteases. Carcinogenesis, Jan 2013; 34: 128 - 138
Toomey et al., Cathepsin B Regulates the Appearance and Severity of Mercury-Induced Inflammation and Autoimmunity. Toxicol. Sci., Dec 2014; 142: 339 - 349.
Yang et al., Overexpression of Vascular Endothelial Growth Factor in the Germinal Matrix Induces Neurovascular Proteases and Intraventricular Hemorrhage. Science Translational Medicine, Jul 2013; 5: 193ra90.
Yi-Hsiang Liao et al., HMG-CoA reductase inhibitors activate caspase-1 in human monocytes depending on ATP release and P2X7 activation. J. Leukoc. Biol., Feb 2013; 93: 289 - 299.

K141 :: Cathepsin K Activity Assay Kit
Chang C-J et al (2009) Am. J. Pathol.; 174: 1837 - 1846.
Christian Sina et. al., Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in mice. Gut, Apr 2013; 62: 520 - 530.
Herrmann, M., et al. (2005) Clin. Chem. 51: 2348-2353.
Kang et al., Osteoprotegerin Expressed by Osteoclasts: An Autoregulator of Osteoclastogenesis. Journal of Dental Research, Nov 2014; 93: 1116 - 1123.
Schmidt S, Kindlin-3-mediated signaling from multiple integrin classes is required for osteoclast-mediated bone resorption. J Cell Biol. 2011 Mar 7;192(5):883-97. Epub 2011 Feb 28.
Toshitake Hirai et al., Cathepsin K Is Involved in Development of Psoriasis-like Skin Lesions through TLR-Dependent Th17 Activation. J. Immunol., May 2013; 190: 4805 - 4811.

K142 :: Cathepsin L Activity Assay Kit
Jan Czyzyk et al., Anti-serpin Antibody-mediated Regulation of Proteases in Autoimmune Diabetes. J. Biol. Chem., Jan 2013; 288: 1612 - 1619.
Liu et al., Autophagy-Lysosome Pathway in Renal Tubular Epithelial Cells Is Disrupted by Advanced Glycation End Products in Diabetic Nephropathy.   J. Biol. Chem., Aug 2015; 290: 20499 - 20510.
Liu et al., Urinary proteins induce lysosomal membrane permeabilization and lysosomal dysfunction in renal tubular epithelial cells. Am J Physiol Renal Physiol, Mar 2015; 308: F639 - F649.
Sugita s et al (2008) J. Immunol.; 181: 7525 - 7536.

K143 :: Cathepsin D Activity Assay Kit
Liu et al., Urinary proteins induce lysosomal membrane permeabilization and lysosomal dysfunction in renal tubular epithelial cells. Am J Physiol Renal Physiol, Mar 2015; 308: F639 - F649.
Park et al., Development of pheochromocytoma in ceramide synthase 2 null mice. Endocr. Relat. Cancer, Aug 2015; 22: 623 - 632.
Vitner, E. et al. Altered Expression and Distribution of Cathepsins in Neuronopathic Forms of Gaucher Disease and in Other Sphingolipidoses. Hum. Mol. Genet. 2010; 10.1093/hmg/ddq273.

K144 :: Cathepsin S Activity Assay Kit
Chang C-J et al (2009) Am. J. Pathol.; 174: 1837 - 1846.
McComb et al., Cathepsins Limit Macrophage Necroptosis through Cleavage of Rip1 Kinase.J. Immunol., Jun 2014; 192: 5671 - 5678.
Taleb, S., et al. (2006) J. Clin. Endocrinol. Metab. 91: 1042-1047.

K145 :: Cathepsin H Activity Fluorometric Assay Kit
Jagessar, S. Anwar et al. (2016) Lymphocryptovirus Infection of Nonhuman Primate B Cells Converts Destructive into Productive Processing of the Pathogenic CD8 T Cell Epitope in Myelin Oligodendrocyte Glycoprotein. J Immunol. 2016 Aug 15;197(4):1074-88.

K148 :: Cathepsin D Inhibitor Screening Kit (Fluorometric)
Jessica L. Schwartz-Roberts et al., GX15-070 (Obatoclax) Induces Apoptosis and Inhibits Cathepsin D- and L–Mediated Autophagosomal Lysis in Antiestrogen-Resistant Breast Cancer Cells. Mol. Cancer Ther., Apr 2013; 12: 448 - 459.

K151 :: Caspase-1 Inhibitor Drug Screening Kit
Wei Y. et al. (2006) Am. J. Physiol. Endocrinol. Metab. E 275-E281.

K152 :: Caspase-2 Inhibitor Drug Screening Kit
Nakajima A et al (2009) PNAS; 106: 12448 - 12452.

K153 :: Caspase-3 Inhibitor Drug Screening Kit
Ramlawi B. et al. (2006) Circulation 114: I-257 - I-263.
Wei Y. et al. (2006) Am. J. Physiol. Endocrinol. Metab. E 275-E281.

K154 :: Caspase-4 Inhibitor Drug Screening Kit
Wei Y. et al. (2006) Am. J. Physiol. Endocrinol. Metab. E 275-E281.

K155 :: Caspase-5 Inhibitor Drug Screening Kit
Wei Y. et al. (2006) Am. J. Physiol. Endocrinol. Metab. E 275-E281.

K156 :: Caspase-6 Inhibitor Drug Screening Kit
Wei Y. et al. (2006) Am. J. Physiol. Endocrinol. Metab. E 275-E281.

K157 :: Caspase-7 Inhibitor Drug Screening Kit
Wei Y. et al. (2006) Am. J. Physiol. Endocrinol. Metab. E 275-E281.

K158 :: Caspase-8 Inhibitor Drug Screening Kit
Teachey D.T. et al. (2006) Blood 108: 1965-1971.
Wallach-Dayan S. et al. (2006) Am. J. Physiol. Lung Cell Mol. Physiol. 290: L790-L796.
Wei Y. et al. (2006) Am. J. Physiol. Endocrinol. Metab. E 275-E281.

K159 :: Caspase-9 Inhibitor Drug Screening Kit
Teachey D.T. et al. (2006) Blood 108: 1965-1971.
Wallach-Dayan S. et al. (2006) Am. J. Physiol. Lung Cell Mol. Physiol. 290: L790-796.
Wei Y. et al. (2006) Am. J. Physiol. Endocrinol. Metab. E 275-E281.

K160 :: Caspase-10 Inhibitor Drug Screening Kit
Wei, Y. et al. (2006) Am. J. Physiol. Endocrinol. Metab. E 275-E281.

K168 :: Granzyme B Activity Fluorometric Assay Kit
Bhela et al., Nonapoptotic and Extracellular Activity of Granzyme B Mediates Resistance to Regulatory T Cell (Treg) Suppression by HLA-DR–CD25hiCD127lo Tregs in Multiple Sclerosis and in Response to IL-6. J. Immunol., Mar 2015; 194: 2180 - 2189.

K170 :: DNA Ladder Isolation
Hong, E. Ionizing Radiation Induces Cellular Senescence of Articular Chondrocytes via Negative Regulation of SIRT1 by p38 Kinase. J. Biol. Chem. 2010; 285: 1283-1295.
Kang SG et al. (2007) J. Biol. Chem. 282: 6090-6097.
Nakajima A et al (2009) PNAS; 106: 12448 - 12452.
Papineni S et al. (2008) Mol. Pharmacol. 73: 553-565.
Sumalatha, Kodandaram et al. (2017) ROS-mediated induction of apoptosis by benzoquinone embelin in human colon adenocarcinoma cells HT-29, J Complement Integr Med. 2017 Mar 17;14(2)
Wang L et al (2008) Cancer Res. 68: 4377-4383.
Yan, B. et al. (260) PNAS 103: 1504-1509.

K172 :: CaspGLOW Fluorescein Active Caspase-12 Staining Kit
Abdel-Latif L. et al. (2006) J. Gen. Virol. 87: 2539-1548.
Alajiz N et al (2008) Clin. Cancer Res. 14: 4891-4897.
Auner, H. W. et. al. The life span of short-lived plasma cells is partly determined by a block on activation of apoptotic caspases acting in combination with endoplasmic reticulum stress. Blood, Nov 2010; 116: 3445 - 3455.
Bian Z-M et al (2008) Invest. Ophthalmol. Vis. Sci.; 49: 5593 - 5601.
Chwa M et al (2008) Invest. Opthalmol. Vis. Sci. 49: 4361-4369.
Cunha DA et al (2008) J. Cell Sci. 121: 2308 - 2318.
Cunha, D. et al. Glucagon-Like Peptide-1 Agonists Protect Pancreatic beta-Cells from Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB. Diabetes. 2009; 58: 2851-2862.
Dolai, S. et. al. Endoplasmic Reticulum Stress-induced Apoptosis in Leishmania through Ca2+-dependent and Caspase-independent Mechanism. J. Biol. Chem., Apr 2011; 286: 13638 - 13646.
Nakajima A et al (2009) PNAS; 106: 12448 - 12452.
Rabik CA et al (2008) J. Pharmacol. Exp. Ther.; 327: 442 - 452.
Trisciuoglio, D et al (2008) J Natl Cancer Inst 100: 1233-1246.

K180 :: CaspGLOW FITC-VAD-FMK Kit
Abdel-Latif, L. et al. (2006) J. Gen Virol. 87: 2539-2548.
Alajiz N et al (2008) Clin. Cancer Res. 14: 4891-4897.
Bahl, K. et al. (2006) J. Immunol. 176: 4284-4295.
Désio Aurélio Farias-de-Oliveira et al., Caspase-8 and caspase-9 mediate thymocyte apoptosis in Trypanosoma cruzi acutely infected mice. J. Leukoc. Biol., Feb 2013; 93: 227 - 234
Cho SH et al (2009) Blood; 10.1182/blood-2008-03-144121.
Li et al., Identification of miR-133b and RB1CC1 as Independent Predictors for Biochemical Recurrence and Potential Therapeutic Targets for Prostate Cancer. Clin. Cancer Res., May 2014; 20: 2312 - 2325.
Lee, Ji Young et al. (2017) Pro-Apoptotic Role of the Human YPEL5 Gene Identified by Functional Complementation of a Yeast moh1Δ Mutation, J Microbiol Biotechnol. 2017 Mar 28;27(3):633-643.
Ohshima, S. (2006) Ann. N.Y. Acad. Sci. 1067: 228-234.
Magari, M. et. al. IL-21–Dependent B Cell Death Driven by Prostaglandin E2, a Product Secreted from Follicular Dendritic Cells. J. Immunol., Oct 2011; 187: 4210 - 4218.
Vogel, Katharina U. et al. (2016) The RNA-Binding Proteins Zfp36l1 and Zfp36l2 Enforce the Thymic β-Selection Checkpoint by Limiting DNA Damage Response Signaling and Cell Cycle Progression, J Immunol. 2016 Oct 1;197(7):2673-85.
Vomhof-DeKrey et al., Cognate interaction with iNKT cells expands IL-10–producing B regulatory cells. PNAS, Oct 2015; 112: 12474 - 12479.
William, J., et al. (2005) J. Immunol. 174: 6879-6887.
Yagi T et al. (2008) PNAS 105: 979 - 984.
Zhang, T. et al. The Pleckstrin Homology Domain Adaptor Protein Bam32/DAPP1 Is Required for Germinal Center Progression. J. Immunol. 2010; 184: 164-172.

K182 :: FITC-VDVAD-FMK
Abdel-Latif, L. et al. (2006) J. Gen. Virol. 87: 2539-1548.
Alajiz N et al (2008) Clin. Cancer Res. 14: 4891 - 4897.
Hui ABY et al (2009) Clin. Cancer Res.; 15: 3716 - 3724.
Ito, E. et al. Potential Use of Cetrimonium Bromide as an Apoptosis-Promoting Anticancer Agent for Head and Neck Cancer. Mol. Pharmacol. 2009; 76: 969-983.
Raquel Espín et al., TNF receptors regulate vascular homeostasis in zebrafish through a caspase-8, caspase-2 and P53 apoptotic program that bypasses caspase-3. Dis. Model. Mech., Mar 2013; 6: 383 - 396.
Yip, K.W. et al. (2006) Mol. Cancer Ther. 5: 2234-2240.

K183 :: CaspGLOW Caspase-3 Staining Kit
Abdel-Latif, L. et al. (2006) J. Gen Virol. 87: 2539-2548.
Alajiz N et al (2008) Clin. Cancer Res. 14: 4891-4897.
Arun Kumar et al., Oncogenic MicroRNA-155 Down-regulates Tumor Suppressor CDC73 and Promotes Oral Squamous Cell Carcinoma Cell Proliferation: IMPLICATIONS FOR CANCER THERAPEUTICS. J. Biol. Chem., Jan 2013; 288: 608 - 618.
Azad et al., Major Pathways of Polymyxin-Induced Apoptosis in Rat Kidney Proximal Tubular Cells. Antimicrob. Agents Chemother., Apr 2015; 59: 2136 - 2143.
Bahl, K. et al (2006) J. Immunol. 176: 4284-4295.
Barbonetti, A. et. al. Energetic Metabolism and Human Sperm Motility: Impact of CB1 Receptor Activation. Endocrinology, Dec 2010; 151: 5882 - 5892.
Cen H et al (2008) FASEB J 10.1096/fj.07-099234.
Chesler, L. et al. (2006) Cancer Res. 66: 8139-8146.
Chiang IT et al., (2017) Hyperforin Inhibits Cell Growth by Inducing Intrinsic and Extrinsic Apoptotic Pathways in Hepatocellular Carcinoma Cells, Anticancer Res, 2017, 37(1)161-167
Cohen J et al (2008) Nephrol. Dial. Transplant. 23: 2512 - 2519.
Frisan, E. et al., Defective nuclear localization of Hsp70 is associated with dyserythropoiesis and GATA-1 cleavage in myelodysplastic syndromes, Blood, Feb 2012; 119: 1532 - 1542.
Herkert B. et. al. The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis J. Cell Biol., Mar 2010; 188: 905 - 918.
Hoetzenecker, W. et al. (2004) J. Invest. Dermatol. 122:673-684.
Hui ABY et al (2009) Clin. Cancer Res.; 15: 3716 - 3724.
Hung et al., Homocysteine facilitates LOX-1 activation and endothelial death through the PKCβ and SIRT1/HSF1 mechanism: relevance to human hyperhomocysteinaemia.  Clin. Sci., Sep 2015; 129: 477 - 487.
HSU, F. T et al., (2017) Regorafenib Induces Apoptosis and Inhibits Metastatic Potential of Human Bladder Carcinoma Cells, Anticancer Research, Jul.2017, 37(9), 4919-4926
Ito, E. et al. Potential Use of Cetrimonium Bromide as an Apoptosis-Promoting Anticancer Agent for Head and Neck Cancer. Mol. Pharmacol. 2009; 76: 969-983.
Jamadar-Shroff V et al (2009) Clin. Cancer Res.; 15: 1269 - 1276.
Jensen et al., Bcl2L13 is a ceramide synthase inhibitor in glioblastoma. PNAS, Mar 2014; 10.1073/pnas.1316700111.
Li et al., Identification of miR-133b and RB1CC1 as Independent Predictors for Biochemical Recurrence and Potential Therapeutic Targets for Prostate Cancer. Clin. Cancer Res., May 2014; 20: 2312 - 2325.
Li X et al. (2007) J. Immunol. 179: 939-949.
Matko Kalac, et. al. HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL. Blood, Nov 2011; 118: 5506 - 5516.
Rabik CA et al (2008) J. Pharmacol. Exp. Ther.; 327: 442 - 452.
Rather et al., Transcriptional Repression of Tumor Suppressor CDC73, Encoding an RNA Polymerase II Interactor, by Wilms Tumor 1 Protein (WT1) Promotes Cell Proliferation: IMPLICATION FOR CANCER THERAPEUTICS. J. Biol. Chem., Jan 2014; 289: 968 - 976.
Singh, N. et al. CD4+ CD25+ Regulatory T Cells Resist a Novel Form of CD28- and Fas-Dependent p53-Induced T cell Apoptosis. J. Immunol. 2010; 184: 94-104.
Stolfi, C. et. al. 2-Methoxy-5-Amino-N-Hydroxybenzamide Sensitizes Colon Cancer Cells to TRAIL-Induced Apoptosis by Regulating Death Receptor 5 and Survivin Expression. Mol. Cancer Ther., Oct 2011; 10: 1969 - 1981.
Tiwari et al., MicroRNA-125a Reduces Proliferation and Invasion of Oral Squamous Cell Carcinoma Cells by Targeting Estrogen-related Receptor α: IMPLICATIONS FOR CANCER THERAPEUTICS. J. Biol. Chem., Nov 2014; 289: 32276 - 32290.
Tzeng, S. et al. (2005) J. Biol. Chem. 280: 35247-35254.
Voorhees PM et al. (2007) Clin. Cancer Res. 13: 6469-6478.
Wang, F. et. al. Evaluation of Chemotherapy Response in VX2 Rabbit Lung Cancer with 18F-Labeled C2A Domain of Synaptotagmin I. J. Nucl. Med., Apr 2011; 52: 592 - 599.
Wang, X. et al. Cellular and Molecular Mechanisms of Photodynamic Hypericin Therapy for Nasopharyngeal Carcinoma Cells. J. Pharmacol. Exp. Ther., Sep 2010; 334: 847 - 853.
Wei et al., Involvement of general control nonderepressible kinase 2 in cancer cell apoptosis by posttranslational mechanisms. Mol. Biol. Cell, Mar 2015; 26: 1044 - 1057.
Yang C et al. (2007) Am. J. Pathol. 170: 722-732.
Yang, L. et. al. Contributions of TRAIL-mediated megakaryocyte apoptosis to impaired megakaryocyte and platelet production in immune thrombocytopenia. Blood, Nov 2010; 116: 4307 - 4316.
Yip, K.W. et al. (2006) Mol. Cancer Ther. 5: 2234-2240.
Zaheen A et al (2009) Blood; 114: 547 - 554.
Gibson, G. et al. Nurse Eggs Form Through an Active Process of Apoptosis in the Spionid Polydora cornuta (Annelida) Integr. Comp. Biol., Apr 2012; 10.1093/icb/ics054.

K188 :: CaspGLOW FITC Caspase-8 Kit
Abdel-Latif, L. et al. (2006) J. Gen Virol. 87: 2539-2548.
Adrienne Anginot et al., Galectin 1 Modulates Plasma Cell Homeostasis and Regulates the Humoral Immune Response. J. Immunol., Jun 2013; 190: 5526 - 5533.
Alajiz N et al (2008) Clin. Cancer Res. 14: 4891-4897.
Azad et al., Major Pathways of Polymyxin-Induced Apoptosis in Rat Kidney Proximal Tubular Cells. Antimicrob. Agents Chemother., Apr 2015; 59: 2136 - 2143.
Bahl, K. et al. (2006) J. Immunol. 176: 4284-4295.
Boulianne et al., AID and Caspase 8 Shape the Germinal Center Response through Apoptosis. J. Immunol., Dec 2013; 191: 5840 - 5847.
Désio Aurélio Farias-de-Oliveira et al., Caspase-8 and caspase-9 mediate thymocyte apoptosis in Trypanosoma cruzi acutely infected mice. J. Leukoc. Biol., Feb 2013; 93: 227 - 234
Hui ABY et al (2009) Clin. Cancer Res.; 15: 3716 - 3724.
Ito, E. et al. Potential Use of Cetrimonium Bromide as an Apoptosis-Promoting Anticancer Agent for Head and Neck Cancer. Mol. Pharmacol. 2009; 76: 969-983.
Jin, Z. et al. (2006) Mol. Cell Biol. 10.1128/MCB.00257-06.
Kongkaneramit L et al (2008) J. Pharmacol. Exp. Ther. 325: 696-977.
Lin K-R et al. (2007) J. Biol. Chem. 282: 21962-21972.
Marchi, E. et al. Pralatrexate Is Synergistic with the Proteosome Inhibitor Bortezomib in in Vitro and in Vivo Models of T-Cell Lymphoid Malignancies.  Clin. Cancer Res., 2010; 16: 3648-3658.
Richter MV and Topham (2007) J. Immunol. 179: 5054-5063.
Sharabi A. et al. (2007) J. Immunol. 179: 4979-4987.
Tzeng, S. et al. (2005) J. Biol. Chem. 280: 35247-35254.
Wang, D. et al. (2006) J. Immunol. 176: 1695-1702.
Wang, X. et al. Cellular and Molecular Mechanisms of Photodynamic Hypericin Therapy for Nasopharyngeal Carcinoma Cells. J. Pharmacol. Exp. Ther., Sep 2010; 334: 847 - 853.
Yang, L. et. al. Contributions of TRAIL-mediated megakaryocyte apoptosis to impaired megakaryocyte and platelet production in immune thrombocytopenia. Blood, Nov 2010; 116: 4307 - 4316.
Zaheen A et al (2009) Blood; 114: 547 - 554.

K189 :: CaspGLOW Active Caspase-9 Staining Kit
Abdel-Latif L. et al. (2006) J. Gen Virol. 87: 2539-2548.
Alajiz N et al (2008) Clin. Cancer Res. 14: 4891-4897.
An, J., et al. (2004) J. Biol. Chem. 279: 19133-19140.
Azad et al., Major Pathways of Polymyxin-Induced Apoptosis in Rat Kidney Proximal Tubular Cells. Antimicrob. Agents Chemother., Apr 2015; 59: 2136 - 2143.
Barbonetti, A. et. al. Energetic Metabolism and Human Sperm Motility: Impact of CB1 Receptor Activation. Endocrinology, Dec 2010; 151: 5882 - 5892.
Désio Aurélio Farias-de-Oliveira et al., Caspase-8 and caspase-9 mediate thymocyte apoptosis in Trypanosoma cruzi acutely infected mice. J. Leukoc. Biol., Feb 2013; 93: 227 - 234
Hui ABY et al (2009) Clin. Cancer Res.; 15: 3716 - 3724.
Ito, E. et al. Potential Use of Cetrimonium Bromide as an Apoptosis-Promoting Anticancer Agent for Head and Neck Cancer. Mol. Pharmacol. 2009; 76: 969-983.
Jamadar-Shroff V et al (2009) Clin. Cancer Res.; 15: 1269 - 1276.
Kongkaneramit L et al (2008) J. Pharmacol. Exp. Ther. 325: 696-977.
Li X et al. (2007) J. Immunol. 179: 939-949.
Lin K-R et al. (2007) J. Biol. Chem. 282: 21962-21972.
Park, W., et al. (2005) Cancer Res. 65: 1197-1206.
Tzeng, S. et al. (2005) J. Biol. Chem. 280: 35247-35254.
Zaheen A et al (2009) Blood; 114: 547 - 554.
Zhnag, X. et. al. Interferon-Description: {gamma} Exacerbates Dry Eye–Induced Apoptosis in Conjunctiva through Dual Apoptotic Pathways. Invest. Ophthalmol. Vis. Sci., Aug 2011; 52: 6279 - 6285.

K190 :: RED-VAD-FMK
Abdel-Latif, L. et al. (2006) J. Gen. Virol. 87: 2539-1548.
Alajiz N et al (2008) Clin. Cancer Res. 14: 4891-4897.
He et al., The distinctive germinal center phase of IgE+ B lymphocytes limits their contribution to the classical memory response. J. Exp. Med., Nov 2013; 210: 2755 - 2771.
Li, Z. Y. et. al. Knockdown Epithelial Membrane Protein 1 Suppresses Human Degenerative Intervertebral Disc–Derived Nucleus Pulposus Cell Proliferation. Cartilage, Jul 2011; 2: 300 - 306.
Moresi V et al (2008) Stem Cells 26: 997-1008.
Pin, Zhi et al. (2016) β-Ecdysterone Protects SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Apoptosis via Mitochondria-Dependent Mechanism: Involvement of p38MAPK–p53 Signaling Pathway, Neurotox Res. 2016 Oct;30(3):453-66.
Veschini L et al. (2007) Blood 109: 2565-2570.
Yu J et al (2008) Infect. Immun.; 10.1128/IAI.01003-08.

K193 :: RED-DEVD-FMK
Ashare A et al. (2007) J. Immunol. 179: 505-513.
Abdel-Latif L. et al. (2006) J. Gen. Virol. 87: 2539-1548.
Alajiz N et al (2008) Clin. Cancer Res. 14: 4891-4897.
Amstutz R. et al (2008) Cancer Res. 68: 3767 - 3776.
Ferranini M et al (2008) J. Immunol.; 181: 5857 - 5864.
Kasinskas RW and Forbes NS (2007) Cancer Res. 67: 3201-3209.
Moresi V et al. (2008) Stem Cells. 10.1634/stemcells.2007-0493.
Zaheen A et al (2009) Blood; 114: 547 - 554.
Yu J et al (2008) Infect. Immun.; 10.1128/IAI.01003-08.
Zaheen A et al (2009) Blood; 114: 547 - 554.

K198 :: RED-IETD-FMK
Abdel-Latif L. et al. (2006) J. Gen. Virol. 87: 2539-1548.
Alajiz N et al (2008) Clin. Cancer Res. 14: 4891-4897.
Chiang IT et al., (2017) Hyperforin Inhibits Cell Growth by Inducing Intrinsic and Extrinsic Apoptotic Pathways in Hepatocellular Carcinoma Cells, Anticancer Res, 2017, 37(1)161-167
Cohen J et al (2008) Nephrol. Dial. Transplant. 23: 2512-2519.
HSU, F. T et al., (2017) Regorafenib Induces Apoptosis and Inhibits Metastatic Potential of Human Bladder Carcinoma Cells, Anticancer Research, Jul.2017, 37(9), 4919-4926
Lin K-R et al. (2007) J. Biol. Chem. 282: 21962-21972.
Moresi V et al. (2008) Stem Cells. 10.1634/stemcells.2007-0493.
Webb, Louise V. et al. (2016) TNF activation of NF-κB is essential for development of single-positive thymocytes J Exp Med. 2016 Jul 25;213(8):1399-407.
Yip K.W. et al. (2006) Mol. Cancer Ther. 5: 2234-2240.
Yu J et al (2008) Infect. Immun.; 10.1128/IAI.01003-08.
Zaheen A et al (2009) Blood; 114: 547 - 554.

K199 :: RED-LEHD-FMK
Abdel-Latif L. et al. (2006) J. Gen. Virol. 87: 2539-1548.
Alajiz NM et al (2008) Clin Cancer Res, 14: 4891 - 4897.
Chwa M et al (2008) Invest. Ophthalmol. Vis. Sci.; 49: 4361 - 4369.
Cohen G et al (2008) Nephrol. Dial. Transplant. 23: 2512-2519.
Lin K-R et al. (2007) J. Biol. Chem. 282: 21962-21972.
Marchi, E. et al. Pralatrexate Is Synergistic with the Proteosome Inhibitor Bortezomib in In Vitro and In Vivo Models of T-Cell Lymphoid Malignancies.  Clin. Cancer Res., 2010; 16: 3648-3658.
Moresi V et al. (2008) Stem Cells. 10.1634/stemcells.2007-0493.
Yip K.W. et al. (2006) Mol. Cancer Ther. 5: 2234-2240.
Yu J et al (2008) Infect. Immun.; 10.1128/IAI.01003-08.
Zaheen A et al (2009) Blood; 114: 547 - 554.

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