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Procathepsin K Antibody

Polyclonal Antibody to detect Procathepsin K in mouse samples
Catalog #: 6667
SKU-Size Size Price Qty
6667-30T 30 μg
$89.00
6667-100 100 μg
$265.00
More Sizes Get Quote

Product Details

Antibody Target Procathepsin K
Alternate Name CTSK, CTSO, CTSO3
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Recombinant mouse Procathepsin K protein (Cat # 1027)
Accession # P43235
Gene ID 1513
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
Purification Affinity Purified Antibody
Species Reactivity Mouse
Application Western blot
Positive Control Western Blot: Recombinant protein
Application & Usage Western blot: 1-4 µg/ml.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cathepsin K is a member of the papain cysteine proteinase family and has been identified as the predominant proteinase responsible for the resorption of the bone matrix. The enzyme cleaves proteins such as collagen type I, collagen type II and osteonectin and therefore plays a role in bone remodeling and resorption in diseases such as osteoporosis, osteolytic bone metastasis and rheumatoid arthritis (Bromme and Okamoto, 1995; Drake, F. et al 1996; Bossard et al, 1996).


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