Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

PRMT4/CARM1 Inhibitor

An inhibitor of Protein Arginine Methyltransferase 4/Coactivator-Associated Arginine Methyltransferase 1
Catalog #: B2808
SKU-Size Size Price Qty
B2808-500 500 μg
$115.00
B2808-1000 1000 μg
$205.00
More Sizes Get Quote

Product Details

Alternate Name Protein Arginine Methyltransferase 4/Coactivator-Associated Arginine Methyltransferase 1 Inhibitor, (3E,5E)-1-benzyl-3,5-bis[(3-bromo-4-hydroxyphenyl)methylidene]piperidin-4-one, CARM1-IN-1
Appearance Crystalline solid
CAS # 1020399-49-8
Molecular Formula C₂₆H₂₁Br₂NO₃
Molecular Weight 555.26
Purity ≥95%
Solubility ~35 mg/ml in DMSO
SMILES C1C(=CC2=CC(=C(C=C2)O)Br)C(=O)C(=CC3=CC(=C(C=C3)O)Br)CN1CC4=CC=CC=C4
InChi InChI=1S/C26H21Br2NO3/c27-22-12-18(6-8-24(22)30)10-20-15-29(14-17-4-2-1-3-5-17)16-21(26(20)32)11-19-7-9-25(31)23(28)13-19/h1-13,30-31H,14-16H2/b20-10+,21-11+
InChi Key KNMFTTWVELIVCC-CLVAPQHMSA-N
PubChem CID 24827559
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

PRMT4/CARM1 Inhibitor is highly selective in blocking the activity of Protein Arginine Methyltransferase 4/Coactivator-Associated Arginine Methyltransferase 1. The IC₅₀ value of inhibition is 7.1 µM. In human prostate adenocarcinoma cancer LNCaP cells, PRMT4/CARM1 inhibitor showed a significant dose-dependent reduction of the prostate-specific antigen promoter activity, at concentrations that did not affect cell viability.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.