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An antagonist of α1-adrenergic receptors
Catalog #: B3055
SKU-Size Size Price Qty
B3055-1 1 mg
B3055-5 5 mg
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Product Details

Alternate Name Furazosin; [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanon
Appearance Solid
CAS # 19216-56-9
Molecular Formula C₁₉H₂₁N₅O₄
Molecular Weight 383.4
Purity ≥95%
Solubility Slightly soluble in DMSO
InChi InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)
PubChem CID 4893
MDL Number MFCD00599563
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


Prazosin is an antagonist of α1-adrenergic receptors (α1-ARs). The affinity estimates (pKi) for inhibition of [3H]-prazosin binding to CHO-K1 cells expressing cloned human α1A, α1B and α1D adrenoceptors are 9.0, 9.9 and 9.5 respectively. It also inhibits α2-ARs with Ki values of 340 nM and 3.7 nM in α2A-AR expressing HT-29 cells and α2B-AR expressing NG108 cells respectively. It is used in the treatment of hypertension, anxiety and post-traumatic stress disorder. It is in clinical trials to prevent cytokine storm in patients with COVID-19.

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