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Pravastatin sodium

A HMG-CoA reductase inhibitor
Catalog #: B2727
SKU-Size Size Price Qty
B2727-10 10 mg
$75.00
B2727-50 50 mg
$275.00
More Sizes Get Quote

Product Details

Alternate Name 1S,2S,6S,7S,8R,8aR-hexahydro-βR,δR,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid, monosodium salt
Peptide Sequence N/A
Appearance White solid
CAS # 81131-70-6
Molecular Formula C₂₃H₃₅O₇ • Na
Molecular Weight 446.51
Purity ≥98%
Solubility ~10 mg/ml DMSO
SMILES CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)[O-])O)O)O.[Na+]
InChi InChI=1S/C23H36O7.Na/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28;/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28);/q;+1/p-1/t13-,14-,16+,17+,18+,19-,20-,22-;/m0./s1
InChi Key VWBQYTRBTXKKOG-IYNICTALSA-M
PubChem CID 16759173
MDL Number MFCD00887601
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Pravastatin is a HMG-CoA (Hydroxymethylglutaryl-coenzyme A reductase) inhibitor that is a ring hydroxylated metabolite of mevastatin (Cat. No. 1694). It is a competitive inhibitor of HMG-CoA reductase with a Ki value of 2.3 nM for the active, open ring form of the molecule. Pravastatin is used to reduce LDL cholesterol and triglyceride levels and increase HDL cholesterol in the prevention of cardiovascular disease.


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