Anti-PPARα Polyclonal Antibody

Affinity purified rabbit polyclonal antibody to detect PPARα expression in human samples
Catalog #: 3585 | abID: ab24509

Product Details

abID ab24509
Antibody Target PPARa
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 25 of human PPARα
Accession # Q07869
Gene ID 5465
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation In phosphate-bufIn phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03% proclin.
Purification Affinity purified
Species Reactivity Human
Application Western blot
Application & Usage The antibody can be used in Western blotting. However, the optimal concentrations should be determined individually.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


PPAR (Peroxisome proliferator-activated receptor) is a member of the nuclear hormone receptor superfamily and functions as a transcriptional activator. PPARα is preferentially expressed in liver, skeletal muscle, heart and kidney. PPARα is involved in regulation of lipid homeostasis. Its ligands include fatty acids, NSAIDs, prostaglandins, leukotriene B4, etc. PPARα transcriptionally regulates a variety of genes for enzymes and proteins involved in fatty acid metabolism and oxidation.

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Hennessy, E. J. et. al. Toll-like Receptor-4 (TLR4) Down-regulates MicroRNA-107, Increasing Macrophage Adhesion via Cyclin-dependent Kinase 6. J. Biol. Chem., Jul 2011; 286: 25531 - 25539.
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