A mTOR inhibitor
Catalog #: 1658 | abID: ab141405

Product Details

abID ab141405
Cat # +Size 1658-1
Size 1 mg
Alternate Name 2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol
Appearance White to off-white solid
CAS # 1092351-67-1
Molecular Formula C₁₆H₁₆N₆O
Molecular Weight 308.34
Purity ≥98% by HPLC
Solubility DMSO (>50 mg/ml)
InChi InChI=1S/C16H16N6O/c1-8(2)22-16-13(15(17)18-7-19-16)14(21-22)12-6-9-5-10(23)3-4-11(9)20-12/h3-8,21,23H,1-2H3,(H2,17,18,19)/b14-12+
PubChem CID 25243800
MDL Number MFCD12196869
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A potent and selective in vitro mTOR inhibitor that targets the ATP domain of mTOR (IC₅₀ = 8 nM). Inhibits other PI 3-Kinases only at much higher concentrations. Recently it has been shown that PP242 is a more effective mTORC1 inhibitor than Rapamycin (Cat. No. 1568-5 & 1568-50).

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