Product Details
| abID | ab141405 |
|---|---|
| Cat # +Size | 1658-1 |
| Size | 1 mg |
| Alternate Name | 2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol |
| Appearance | White to off-white solid |
| CAS # | 1092351-67-1 |
| Molecular Formula | C₁₆H₁₆N₆O |
| Molecular Weight | 308.34 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (>50 mg/ml) |
| SMILES | CC(C)N1C2=C(C(=C3C=C4C=C(C=CC4=N3)O)N1)C(=NC=N2)N |
| InChi | InChI=1S/C16H16N6O/c1-8(2)22-16-13(15(17)18-7-19-16)14(21-22)12-6-9-5-10(23)3-4-11(9)20-12/h3-8,21,23H,1-2H3,(H2,17,18,19)/b14-12+ |
| InChi Key | MTICIDWIKCANDD-WYMLVPIESA-N |
| PubChem CID | 25243800 |
| MDL Number | MFCD12196869 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
A potent and selective in vitro mTOR inhibitor that targets the ATP domain of mTOR (IC₅₀ = 8 nM). Inhibits other PI 3-Kinases only at much higher concentrations. Recently it has been shown that PP242 is a more effective mTORC1 inhibitor than Rapamycin (Cat. No. 1568-5 & 1568-50).
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