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Posaconazole

A triazole antifungal agent
Catalog #: B2102

In stock

SKU-Size Size Price Qty
B2102-5 5 mg
$115.00
B2102-25 25 mg
$455.00
More Sizes Get Quote

Product Details

Alternate Name 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol; SCH56592
Appearance White to off-white solid
CAS # 171228-49-2
Molecular Formula C₃₇H₄₂F₂N₈O₄
Molecular Weight 700.8
Purity ≥98%
Solubility DMSO (0.5 mg/ml)
SMILES CCC(C(C)O)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5CC(OC5)(CN6C=NC=N6)C7=C(C=C(C=C7)F)F
InChi InChI=1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37-/m0/s1
InChi Key RAGOYPUPXAKGKH-XAKZXMRKSA-N
PubChem CID 468595
MDL Number MFCD00941162
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Posaconazole is a triazole antifungal agent that is structurally related to itraconazole and displays activity against Candida species, Aspergillus species, Cryptococcus neoformans, the zygomycetes, and other filamentous fungi. Randomized, double-blind trials have shown posaconazole to be at least as efficacious as fluconazole for the prevention of invasive fungal infections in immunocompromised patients.


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