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A NLRP3 Inflammasome inhibitor
Catalog #: B3380
SKU-Size Size Price Qty
B3380-1G 1 g
B3380-5G 5 g
More Sizes Get Quote

Product Details

Alternate Name Etosuximida 2-Ethyl-2-methylsuccinimide Zarontin
Appearance White to off-white solid
CAS # 65914-17-2
Molecular Formula C₂₀H₂₂O₈
Molecular Weight 390.38
Purity ≥97% by HPLC
Solubility DMSO
InChi InChI=1S/C20H22O8/c21-10-16-17(24)18(25)19(26)20(28-16)27-15-8-12(7-14(23)9-15)2-1-11-3-5-13(22)6-4-11/h1-9,16-26H,10H2/b2-1+/t16-,17-,18+,19-,20-/m1/s1
PubChem CID 5281718
MDL Number MFCD00210592
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Polydatin is a monocrystalline compound isolated from the root and rhizome of Polygonum cuspidatum Sieb. et Zucc. (Polygonaceae). It displays antioxidant and anti-inflammatory effects. Polydatin inhibits NLRP3 Inflammasome in Dry Eye Disease by attenuating oxidative stress and inhibiting the NF-κB Pathway.

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