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Podophyllotoxin

A potent inhibitor of microtubule assembly and DNA topoisomerase II
Catalog #: 2767
SKU-Size Size Price Qty
2767-50 50 mg
$65.00
2767-250 250 mg
$155.00
More Sizes Get Quote

Product Details

Alternate Name (10R,11R,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.03,7.011,15]hexadeca-1,3(7),8-trien-12-one ; (-)-Podophyllotoxin; Condyline; Condylox; NSC 24818; Podofilox;PPT
Appearance White to off-white solid
CAS # 518-28-5, 4354-76-1
Molecular Formula C₂₂H₂₂O₈
Molecular Weight 414.41
Purity ≥98% by HPLC
Solubility EtOH (>35 mg/ml)
SMILES COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O
InChi InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1
InChi Key YJGVMLPVUAXIQN-XVVDYKMHSA-N
PubChem CID 10607
MDL Number MFCD00075290
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Podophyllotoxin is a potent inhibitor of microtubule assembly and DNA topoisomerase II. Displays anticancer properties. Also antiviral and antihelminthic.


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