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Podocalyxin, mouse recombinant

Catalog #: P1033

In stock

SKU-Size Size Price Qty
P1033-10 10 μg
$105.00
P1033-50 50 µg
$495.00
More Sizes Get Quote

Product Details

Alternate Name AW121214, Ly102, PC, PCLP-1, Pclp1, Podxl
Gene Symbol Podxl
Gene ID 27205
Accession # Q9R0M4
Source Baculovirus
Appearance Liquid
Physical Form Description In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Weight 41 kDa
Purity by SDS-PAGE > 95%
Endotoxin Level < 1.0 EU per/μg
Amino Acid Sequence HNGNETSTSA IKSSTVQSHQ SATTSTEVTT GHPVASTLAS TQPSNPTPFT TSTQSPSMPT STPNPTSNQS GGNLTSSVSE VDKTKTSSPSSTAFTSSSGQ TASSGGKSGD SFTTAPTTTL GLINVSSQPT DLNTTSKLLS TPTTDNTTSP QQPVDSSPST ASHPVGQHTP AAVPSSSGSTPSTDNSTLTW KPTTHKPLGT SEATQPLTSQ TPGITTLPVS TLQQSMASTV GTTT
Handling Centrifuge the vial prior to opening.
Storage Conditions -70°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

PODXL, also known as Podocalyxin, is a heavily glycosylated transmembrane sialoprotein in the CD34 and endoglycan family. This protein involved in the regulation of both adhesion and cell morphology and cancer progression. It has to function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Also, it acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Recombinant mouse PODXL, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.


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