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PKC Antibody

Catalog #: 3450
SKU-Size Size Price Qty
3450-30T 30 µg
$89.00
3450-100 100 µg
$265.00
More Sizes Get Quote

Product Details

Antibody Target PKC
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide corresponding to the C-terminus of mouse PKC β1
Accession # EDL17279.1
Gene ID 18751
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 60-75 kDa PKC βisoforms from samples of human, mouse, rat, pig and bovine origins. A 40 kDa band can also be detected, presumabl
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

PKC (Protein kinase C) is a calcium-dependent and phospholipid-dependent enzyme that is activated in vivo by the lipid diacylglycerol. PKC has been shown to be involved in signal transduction and various aspects of neoplastic transformation. PKC contains an amino terminal regulatory domain and a carboxy terminal catalytic domain joined by a hinge region. Cleavage of protein kinase C in vitro results in the generation of two functional fragments corresponding to these two domains.


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