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PKA cg, Active

Target for the small GTP binding proteins
Catalog #: 7728
$295.00

Product Details

Cat # +Size 7728-5
Size 5 μg
Alternate Name PKA, cAMP-dependent protein kinase catalytic subunit gamma
Gene Symbol PKA
Gene ID 5568
Accession # NM_002732.
Source Baculovirus (Sf9 insect cells)
Appearance Liquid
Physical Form Description Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Molecular Weight 65.0 kDa
Purity by SDS-PAGE ≥90%
Handling Centrifuge the vial prior to opening.
Storage Conditions -80°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

PKA C-γ (PKAcg) is a third isoform of the catalytic subunit of cAMP-dependent protein kinase. It was isolated from a human testis cDNA library and was clearly derived from a gene distinct from C-α and C-β and showed tissue-specific expression. Whereas at the amino acid level C-α and C-β showed 93% homology, C-γ showed only about 80% homology to both C-α and C-β (1). The PRKACG gene is intronless, contains remnants of a poly (A) tail, is flanked by direct repeats, and is co-linear with the PRKACA gene(2).


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