PJ-34 hydrochloride

A potent poly(ADP-ribose) polymerase (PARP) inhibitor
Catalog #: 2319 | abID:

Product Details

Alternate Name N-(6-Oxo-5,6-dihydro-phenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride
Appearance Pale yellow solid
CAS # 344458-15-7
Molecular Formula C₁₇H₁₇N₃O₂.HCl
Molecular Weight 331.8
Purity ≥98% by HPLC
Solubility DMSO (~30 mg/ml) or H₂O (~ 30 mg/ml)
InChi InChI=1S/C17H17N3O2.ClH.H2O/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15;;/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22);1H;1H2
PubChem CID 16219859
MDL Number MFCD03452993
Handling Protect from air and moisture
Storage Conditions -20 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A potent, water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor (EC₅₀ = 20 nM). Inhibits peroxynitrite-induced cell necrosis and displays significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Suppresses cell growth in liver cancer cells.

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