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Pirarubicin

An anticancer drug
Catalog #: B2216
SKU-Size Size Price Qty
B2216-5 5 mg
$145.00
B2216-25 25 mg
$575.00
More Sizes Get Quote

Product Details

Alternate Name (8S,10S)-10-(((2R,4S,5S,6S)-4-amino-6-methyl-5-(((S)-tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
Appearance Red solid
CAS # 72496-41-4
Molecular Formula C₂₃H₃₇NO₁₂
Molecular Weight 627.64
Purity ≥98% by HPLC
Solubility EtOH (~25 mg/ml)
SMILES CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)OC6CCCCO6
InChi InChI=1S/C32H37NO12/c1-14-31(45-21-8-3-4-9-42-21)17(33)10-22(43-14)44-19-12-32(40,20(35)13-34)11-16-24(19)30(39)26-25(28(16)37)27(36)15-6-5-7-18(41-2)23(15)29(26)38/h5-7,14,17,19,21-22,31,34,37,39-40H,3-4,8-13,33H2,1-2H3/t14-,17-,19-,21-,22-,31+,32-/m0/s1
InChi Key KMSKQZKKOZQFFG-HSUXVGOQSA-N
PubChem CID 636397
MDL Number MFCD00869742
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Pirarubicin is an analog of doxorubicin, that acts as an antineoplastic drug. Pirarubicin is transported into cells via a sodium-dependent nucleoside transporter. It is used to intercalate DNA and inhibit the activity of topoisomerase II and induce DNA crosslinking.


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