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Piperine

A potent antioxidant and antiinflammatory agent
Catalog #: B2086
SKU-Size Size Price Qty
B2086-1G 1 g
$65.00
B2086-5G 5 g
$195.00
More Sizes Get Quote

Product Details

Alternate Name (2E,4E)-5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one; N-Piperoylpiperidin; NSC 21727; Bioperine
Appearance White to off-white solid
CAS # 94-62-2
Molecular Formula C₁₇H₁₉NO₃
Molecular Weight 285.354
Purity ≥98% by HPLC
Solubility DMSO (~10 mg/ml)
SMILES C1CCN(CC1)C(=O)C=CC=CC2=CC3=C(C=C2)OCO3
InChi InChI=1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+
InChi Key MXXWOMGUGJBKIW-YPCIICBESA-N
PubChem CID 638024
MDL Number MFCD00005839
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Piperine is the primary pungent alkaloid isolated from the fruit of black peppercorns. It displays a variety of therapeutic activities such as anti-oxidant, anti-inflammatory, immunomodulatory, anti-asthmatic, anti-convulsant, anti-mutagenic, antimycobacterial, anti-amoebic, and anti-cancer activities. Piperine affects cytochrome P450 (CYP) isoforms, inhibiting CYP3A species (Ki ~ 5 µM) and increasing expression of CYP1A and CYP2B in liver. It also has a biphasic effect on P-glycoprotein activity.


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