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Pimozide

A Stat5 inhibitor

WARNING: This product can expose you to chemicals including Pimozide, which is [are] known to the State of California to cause birth defects or other reproductive harm.  For more information go to  www.P65Warnings.ca.gov.
Catalog #: 1887
SKU-Size Size Price Qty
1887-50 50 mg
$70.00
1887-250 250 mg
$265.00
More Sizes Get Quote

Product Details

Alternate Name 1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
Appearance White solid
CAS # 2062-78-4
Molecular Formula C₂₈H₂₉F₂N₃O
Molecular Weight 461.55
Purity ≥98% by TLC
Solubility DMSO (100 mM)
SMILES C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F
InChi InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)
InChi Key YVUQSNJEYSNKRX-UHFFFAOYSA-N
PubChem CID 16362
MDL Number MFCD00055081
Handling Protect from air and light
Storage Conditions 2-8°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. An antipsychotic drug and D2 dopamine receptor antagonist; binds with high affinity to the cloned 5-HT7 receptor. A Stat5 inhibitor; decreases Stat5 tyrosine phosphorylation, but does not affect Bcr-Abl or other tyrosine kinases.


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