Product Details
| Alternate Name | PIK75 , PIK75; PIK 75; PIK-75 Hydrochloride; PIK75 Hydrochloride; PIK 75 Hydrochloride; (E)-N'-((6-bromoH-imidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazide hydrochloride; PIK-75 Hydrochloride; PIK75 Hydrochloride; PIK 75 Hydrochloride |
|---|---|
| Appearance | Solid |
| CAS # | 372196-77-5 |
| Molecular Formula | C₁₆H₁₅BrClN₅O₄S |
| Molecular Weight | 488.74 |
| Purity | >98% |
| Solubility | DMSO |
| SMILES | CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N(C)N=CC2=CN=C3N2C=C(C=C3)Br.Cl |
| InChi | InChI=1S/C16H14BrN5O4S.ClH/c1-11-3-5-13(22(23)24)7-15(11)27(25,26)20(2)19-9-14-8-18-16-6-4-12(17)10-21(14)16;/h3-10H,1-2H3;1H/b19-9+; |
| InChi Key | VOUDEIAYNKZQKM-MYHMWQFYSA-N |
| PubChem CID | 45265864 |
| MDL Number | MFCD12546130 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
PIK-75 is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM.
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