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PIK-294

A potent PI3K p110δ inhibitor
Catalog #: 2614
SKU-Size Size Price Qty
2614-5 5 mg
$115.00
2614-25 25 mg
$460.00
More Sizes Get Quote

Product Details

Alternate Name 2-[[4-Amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone
Appearance Crystalline solid
CAS # 900185-02-6
Molecular Formula C₂₈H₂₃N₇O₂
Molecular Weight 489.53
Purity >98% by HPLC
Solubility DMSO (>60 mg/ml)
SMILES O=C1N(C2=CC=CC=C2C)C(CN3N=C(C4=CC=CC(O)=C4)C5=C(N)N=CN=C53)=NC6=C1C(C)=CC=C6
InChi InChI=1S/C28H23N7O2/c1-16-7-3-4-12-21(16)35-22(32-20-11-5-8-17(2)23(20)28(35)37)14-34-27-24(26(29)30-15-31-27)25(33-34)18-9-6-10-19(36)13-18/h3-13,15,36H,14H2,1-2H3,(H2,29,30,31)
InChi Key WFSLJOPRIJSOJR-UHFFFAOYSA-N
PubChem CID 24905149
Handling Protect from air and light
Storage Conditions -20 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

PIK-294 is a highly potent and selective p110δ inhibitor (IC₅₀ of 10 nM). Displays 1000-, 49- and 16-fold less potency against PI3Kα/β/γ, respectively.


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