Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

PI3K-α Inhibitor

A potent and selective PI3Kα inhibitor
Catalog #: B1869
SKU-Size Size Price Qty
B1869-5 5 mg
B1869-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name 3-(4-Morpholinothieno[3,2-d]pyrimidin-2-yl)phenol
Appearance White solid
CAS # 371943-05-4
Molecular Formula C₁₆H₁₅N₃O₂S
Molecular Weight 313.4
Purity ≥98% by HPLC
Solubility DMSO (>25 mg/ml)
InChi InChI=1S/C16H15N3O2S/c20-12-3-1-2-11(10-12)15-17-13-4-9-22-14(13)16(18-15)19-5-7-21-8-6-19/h1-4,9-10,20H,5-8H2
PubChem CID 9901372
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


PI3Kα inhibitor is a potent and selective inhibitor of PI3Kα with IC₅₀ values of 2, 16, 660, and 220 nM for the α, β, γ, and 2Cβ isoforms, respectively. It inhibits PKA, KDR, PKCα, and cyclin E/Cdk2 significantly less effectively (IC₅₀ = 91, 3.4, 466, and 28 µM, respectively). PI3Kα inhibitor inhibits A375 melanoma cell proliferation with an IC₅₀ value of 580 nM.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.