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PI3 kinase Antibody

Catalog #: 3959
SKU-Size Size Price Qty
3959-30T 30 µg
$89.00
3959-100 100 µg
$245.00
More Sizes Get Quote

Product Details

Antibody Target PI3 kinase
Alternate Name PIK3CA; MGC142161; MGC142163; PI3K
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 505 of mouse P13 kinase.
Accession # NP_032865
Gene ID 18706
Appearance Colorless liquid
Concentration 0.5mg/ml
Formulation 0.5 mg/ml affinity purified rabbit anti-PI3-Kinase polyclonal antibody in PBS, pH 7.2, 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03% proclin
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot, Immunohistochemistry
Positive Control Western Blot: Jurkat cell lysate. IHC: colon tissue
Application & Usage The antibody can be used for Western blot analysis (1-4 µg/ml) and Immunohistochemistry (5 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide (Cat.# 3959BP-50) is available separately.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Phosphatidylinositol 3-kinase (PI 3-kinase), is a phosphoinositide-specific protein kinase that plays a central role in mitogenic signal transduction leading to cellular regulation, cell growth and differentiation, and oncogenesis. PI 3-kinase associates with, and is activated by a wide range of tyrosine kinase receptors including EGF, PDGF, CSF-1, erbB-3 and insulin receptor, non-receptor protein-tyrosine kinases of the src family (e.g. pp60src), and crk and abl proto-oncogene products. PI 3-kinase is involved in signal transduction in terminally differentiated, activated cells like platelets and neutrophils.


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