Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


based on 1 citations in multiple journalsPI-10314.1 4
A PI3 Kinase inhibitor
Catalog #: 1728
SKU-Size Size Price Qty
1728-1 1 mg
1728-5 5 mg
More Sizes Get Quote

Product Details

Alternate Name 3-(4-(4-Morpholinyl)pyrido[3′,2′:4,5]furo[3,2-d]pyrimidin-2-yl)phenol
Appearance Off-white solid
CAS # 371935-74-9
Molecular Formula C₁₉H₁₆N₄O₃
Molecular Weight 348.36
Purity ≥98% by HPLC
Solubility DMSO (50 mM)
InChi InChI=1S/C19H16N4O3/c24-13-4-1-3-12(11-13)17-21-15-14-5-2-6-20-19(14)26-16(15)18(22-17)23-7-9-25-10-8-23/h1-6,11,24H,7-10H2
PubChem CID 9884685
MDL Number MFCD11983145
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110α), and mTOR. The IC₅₀ values are 2, 8, 20, 26, 48, 83, 88, 150 nM for DNA-PK, p110α, mTORC1, PI3-KC2β, p110δ, mTORC2, p110β, and p110γ, respectively. Inhibits growth of human tumor xenografts in mice in vivo.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.
Jacque et al., BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival. J. Exp. Med., Jun 2015; 212: 883 - 892.15604.
For more citations of this product click here