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A major bioactive lignan found in many Phyllanthus species
Catalog #: B2777
SKU-Size Size Price Qty
B2777-1 1 mg
B2777-5 5 mg
More Sizes Get Quote

Product Details

Alternate Name (2S,3S)-(+)-1,4-Dimethoxy-2,3-diveratrylbutane; NSC-619043
Peptide Sequence N/A
Appearance Crystalline solid
CAS # 10351-88-9
Molecular Formula C₂₄H₃₄O₆
Molecular Weight 418.52
Purity ≥98%
Solubility ~10 mg/ml DMSO
SMILES COC1=C(OC)C=C(C[[email protected]]([[email protected]@](CC2=CC=C(OC)C(OC)=C2)([H])COC)([H])COC)C=C1
InChi InChI=1S/C24H34O6/c1-25-15-19(11-17-7-9-21(27-3)23(13-17)29-5)20(16-26-2)12-18-8-10-22(28-4)24(14-18)30-6/h7-10,13-14,19-20H,11-12,15-16H2,1-6H3/t19-,20-/m1/s1 Computed by InChI 1.0.5 (PubChem release 2019.06.18)
PubChem CID 358901
MDL Number MFCD17166965
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Phyllanthin is a major bioactive lignan found in many Phyllanthus species. It displays various biochemical and pharmacological properties especially on its hepatoprotective effects. It scavenges DPPH radicals with an IC50 value of 7.4 µM and, at 30 µM, has been shown to alleviate carbon tetrachloride-induced lipid peroxidation and cytotoxicity in a human hepatoma HepG2 cell line.

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