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PHT-427

A potent Akt and PDPK1 inhibitor
Catalog #: 2465
SKU-Size Size Price Qty
2465-10 10 mg
$105.00
2465-50 50 mg
$415.00
More Sizes Get Quote

Product Details

Alternate Name 4-Dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide
Appearance White to off-white solid
CAS # 1191951-57-1
Molecular Formula C₂₀H₃₁N₃O₃S₂
Molecular Weight 409.61
Purity ≥98% by HPLC
Solubility DMSO (> 80 mg/ml)
SMILES CCCCCCCCCCCCC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2
InChi InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)
InChi Key BYWWNRBKPCPJMG-UHFFFAOYSA-N
PubChem CID 44240850
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A potent Akt and PDPK1 (3-Phosphoinositide Dependent Protein Kinase 1) inhibitor. PH 427 binds to the pleckstrin homology (PH) domain of Akt and PDPK1 signaling with significant in vivo antitumor activity and minimal toxicity.


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