Product Details
| Alternate Name | 4-Dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide |
|---|---|
| Appearance | White to off-white solid |
| CAS # | 1191951-57-1 |
| Molecular Formula | C₂₀H₃₁N₃O₃S₂ |
| Molecular Weight | 409.61 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (> 80 mg/ml) |
| SMILES | CCCCCCCCCCCCC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2 |
| InChi | InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23) |
| InChi Key | BYWWNRBKPCPJMG-UHFFFAOYSA-N |
| PubChem CID | 44240850 |
| Handling | Protect from air and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
A potent Akt and PDPK1 (3-Phosphoinositide Dependent Protein Kinase 1) inhibitor. PH 427 binds to the pleckstrin homology (PH) domain of Akt and PDPK1 signaling with significant in vivo antitumor activity and minimal toxicity.
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