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Phospho TGFBR2 (Ser225) Antibody

Affinity purified rabbit polyclonal antibody to detect phosphorylation of TGFBR2 at Ser225 in human, mouse, rat, porcine, rabbit samples
Catalog #: A1975
$325.00

Product Details

Size 100 µl
Antibody Target Phospho TGFBR2 (Ser225)
Alternate Name TGF-beta receptor type-2; TGFR-2; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TbetaR-II
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Accession # P37173
Gene ID 7048
Appearance Colorless liquid
Formulation In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
Purification Affinity purified
Species Reactivity Porcine, Rat, Rabbit, Mouse, Human
Application Western Blotting
Application & Usage WB 1:500 - 1:1000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.


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