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Phospho S6K1 (Thr421) Antibody

Affinity purified rabbit polyclonal antibody to detect phosphorylation of S6K1 at Thr421 in human, mouse, rat, bovine, and rabbit samples
Catalog #: A1967
$285.00

Product Details

Size 100 µl
Antibody Target Phospho S6K1 (Thr421)
Alternate Name STK14A; Ribosomal protein S6 kinase beta-1; S6K-beta-1; S6K1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KA
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Accession # P23443
Gene ID 6198
Appearance Colorless liquid
Formulation In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
Purification Affinity purified
Species Reactivity Rabbit, Bovine, Rat, Mouse, Human
Application Immunohistochemistry (IHC), Western Blotting
Application & Usage WB 1:500 - 1:1000, IHC 1:100 - 1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.


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