Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Phospho-PKC ζ (Thr 410) Antibody

Polyclonal antibody to detect Phospho-PKC ζ (Thr 410) in human, mouse and rat samples.
Catalog #: A1130

Product Details

Cat # +Size A1130-100
Size 100 µl
Antibody Target PRKCZ
Alternate Name PRKCZ; PKC2; Protein kinase C zeta type; nPKC-zeta
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthesized peptide derived from human PKC ζ around the phosphorylation site of Thr 410.
Accession # Q05513 (Human); Q02956 (Mouse); P09217 (Rat)
Gene ID 5590 (Human); 18762 (Mouse); 25522 (Rat)
Appearance Colorless liquid
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Purification Affinity-purified using epitope specific immunogen.
Species Reactivity Human, mouse and rat
Application WB, IHC, IF, ELISA
Positive Control WB: 823, Hela, PC-3, MCF-7, 22RV1 cell lysate
Application & Usage WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Calcium- and diacylglycerol-independent serine/threonine-protein kinase that functions in phosphatidylinositol 3-kinase (PI3K) pathway and mitogen-activated protein (MAP) kinase cascade, and is involved in NF-kappa-B activation, mitogenic signaling, cell proliferation, cell polarity, inflammatory response and maintenance of long-term potentiation (LTP). Upon lipopolysaccharide (LPS) treatment in macrophages, or following mitogenic stimuli, functions downstream of PI3K to activate MAP2K1/MEK1-MAPK1/ERK2 signaling cascade independently of RAF1 activation. Required for insulin-dependent activation of AKT3, but may function as an adapter rather than a direct activator. Upon insulin treatment may act as a downstream effector of PI3K and contribute to the activation of translocation of the glucose transporter SLC2A4/GLUT4 and subsequent glucose transport in adipocytes.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.