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Phospho-p38 MAPK Antibody

Catalog #: 3438
$345.00

Product Details

Cat # +Size 3438-100
Size 100 µg
Antibody Target Phospho-p38 MAPK
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic phospho-peptide surrounding amino acid Thr180/Tyr182 of human p38 MAP kinase
Accession # ACI00233
Gene ID 1432
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot, Immunoprecipitation, Immunohistochemistry
Application & Usage Western blotting (0.5-4 μg/ml), immunoprecipitation (10-20 mg/ml) and Immunohistochemistry (10-20 μg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 43 kDa phosphorylated p38 (Thr180/Tyr182) MAP kinase o
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

p38 MAP kinase is the mammalian homologue of the yeast HOG kinase and participates in a cascade controlling cellular responses to cytokines and stress. Like the SAPK/JNK pathway, p38 MAP kinase is activated by a variety of cellular tresses including inflammatory cytokines,UV light and growth factors, etc. Activated p38 MAP kinase has been shown to phosphorylate and activate MAPKAP kinase-2 and to phosphorylate the transcription factors ATF-2 and Max.


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